Next Article in Journal
Low-Complexity High-Order Propagator Method for Near-Field Source Localization
Next Article in Special Issue
A Schiff Base Fluorescence Enhancement Probe for Fe(III) and Its Sensing Applications in Cancer Cells
Previous Article in Journal
Cooperative Spectrum Sensing with Coded and Uncoded Decision Fusion under Correlated Shadowed Fading Report Channels
Open AccessCommunication

Single-Step Detection of the Influenza Virus Hemagglutinin Using Bacterially-Produced Quenchbodies

by 1, 2,3,4 and 4,*
1
Department of Biological and Chemical Engineering, College of Science and Technology, Hongik University, Sejong-si 30016, Korea
2
Key Laboratory of Biological Medicine in Universities of Shandong Province, School of Bioscience and Technology, Weifang Medical University, Weifang 261042, China
3
Tokyo Tech World Research Hub Initiative (WRHI), Institute of Innovative Research, Tokyo Institute of Technology, 4259 Nagatsuta-cho, Midori-ku, Yokohama, Kanagawa 226-8503, Japan
4
Laboratory for Chemistry and Life Science, Institute for Innovative Research, Tokyo Institute of Technology, Yokohama 226-8503, Japan
*
Author to whom correspondence should be addressed.
Sensors 2019, 19(1), 52; https://doi.org/10.3390/s19010052
Received: 15 October 2018 / Revised: 5 December 2018 / Accepted: 20 December 2018 / Published: 23 December 2018
(This article belongs to the Special Issue Fluorescent Biosensors 2019)
We have successfully generated a Quenchbody that enables the detection of the influenza virus hemagglutinin (HA), in a simple and convenient manner. By two-site labeling of the bacterially-produced anti-HA Fab with ATTO520, its fluorescence intensity was increased to 4.4-fold, in the presence of a nanomolar concentration of H1N1 HA. Our results indicate the potential use of this Quenchbody, as a sensor for the simple in situ detection of influenza A virus. View Full-Text
Keywords: influenza A; hemagglutinin; H1N1; Quenchbody; immunosensor influenza A; hemagglutinin; H1N1; Quenchbody; immunosensor
Show Figures

Graphical abstract

MDPI and ACS Style

Jeong, H.-J.; Dong, J.; Ueda, H. Single-Step Detection of the Influenza Virus Hemagglutinin Using Bacterially-Produced Quenchbodies. Sensors 2019, 19, 52.

AMA Style

Jeong H-J, Dong J, Ueda H. Single-Step Detection of the Influenza Virus Hemagglutinin Using Bacterially-Produced Quenchbodies. Sensors. 2019; 19(1):52.

Chicago/Turabian Style

Jeong, Hee-Jin; Dong, Jinhua; Ueda, Hiroshi. 2019. "Single-Step Detection of the Influenza Virus Hemagglutinin Using Bacterially-Produced Quenchbodies" Sensors 19, no. 1: 52.

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Search more from Scilit
 
Search
Back to TopTop