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Sensors 2018, 18(2), 518; https://doi.org/10.3390/s18020518

Infrared Thermography as a Non-Invasive Tool to Explore Differences in the Musculoskeletal System of Children with Hemophilia Compared to an Age-Matched Healthy Group

1
Practice for Rehabilitation, Prevention and Orthopedics, 53225 Bonn, Germany
2
Dr. von Hauner Children’s Hospital, University of Munich, 80337 Munich, Germany
3
Institute of Sugar Beet Research, 37079 Göttingen, Germany
These authors contributed equally to this work.
*
Author to whom correspondence should be addressed.
Received: 24 November 2017 / Revised: 6 February 2018 / Accepted: 7 February 2018 / Published: 8 February 2018
(This article belongs to the Special Issue Sensors for Health Monitoring and Disease Diagnosis)
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Abstract

Recurrent joint bleeds and silent bleeds are the most common clinical feature in patients with hemophilia. Every bleed causes an immediate inflammatory response and is the leading cause of chronic crippling arthropathy. With the help of infrared thermography we wanted to detect early differences between a group of clinical non-symptomatic children with hemophilia (CWH) with no history of clinically detected joint bleeds and a healthy age-matched group of children. This could help to discover early inflammation and help implement early treatment and preventative strategies. It could be demonstrated that infrared thermography is sensitive enough to detect more signs of early inflammatory response in the CWH than in healthy children. It seems to detect more side differences in temperature than clinical examination of silent symptoms detects tender points. Silent symptoms/tender points seem to be combined with early local inflammation. Using such a non-invasive and sensor-based early detection, prevention of overloading and bleeding might be achieved. View Full-Text
Keywords: hemophilia; infrared thermography; non-invasive; silent bleeds; hot-spot hemophilia; infrared thermography; non-invasive; silent bleeds; hot-spot
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Seuser, A.; Kurnik, K.; Mahlein, A.-K. Infrared Thermography as a Non-Invasive Tool to Explore Differences in the Musculoskeletal System of Children with Hemophilia Compared to an Age-Matched Healthy Group. Sensors 2018, 18, 518.

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