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Plasmonic Gold Nanostars for Multi-Modality Sensing and Diagnostics

Fitzpatrick Institute for Photonics, Duke University, Durham, NC 27708, USA
Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA
Department of Chemistry, Duke University, Durham, NC 27708, USA
Department of Radiology & Biomedical Research Imaging Center, University of North Carolina at Chapel Hill, NC 27510, USA
Author to whom correspondence should be addressed.
Sensors 2015, 15(2), 3706-3720;
Received: 13 January 2015 / Accepted: 30 January 2015 / Published: 5 February 2015
Gold nanostars (AuNSs) are unique systems that can provide a novel multifunctional nanoplatform for molecular sensing and diagnostics. The plasmonic absorption band of AuNSs can be tuned to the near infrared spectral range, often referred to as the “tissue optical window”, where light exhibits minimal absorption and deep penetration in tissue. AuNSs have been applied for detecting disease biomarkers and for biomedical imaging using multi-modality methods including surface-enhanced Raman scattering (SERS), two-photon photoluminescence (TPL), magnetic resonance imaging (MRI), positron emission tomography (PET), and X-ray computer tomography (CT) imaging. In this paper, we provide an overview of the recent development of plasmonic AuNSs in our laboratory for biomedical applications and highlight their potential for future translational medicine as a multifunctional nanoplatform. View Full-Text
Keywords: gold nanostars; plasmonics; multifunctional; sensing gold nanostars; plasmonics; multifunctional; sensing
MDPI and ACS Style

Liu, Y.; Yuan, H.; Kersey, F.R.; Register, J.K.; Parrott, M.C.; Vo-Dinh, T. Plasmonic Gold Nanostars for Multi-Modality Sensing and Diagnostics. Sensors 2015, 15, 3706-3720.

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