Next Article in Journal
Application of Composite Dictionary Multi-Atom Matching in Gear Fault Diagnosis
Next Article in Special Issue
An Electronic Nose for Reliable Measurement and Correct Classification of Beverages
Previous Article in Journal
Adaptive Broadcasting Method Using Neighbor Type Information in Wireless Sensor Networks
Previous Article in Special Issue
Roughness Encoding in Human and Biomimetic Artificial Touch: Spatiotemporal Frequency Modulation and Structural Anisotropy of Fingerprints
Article Menu

Export Article

Open AccessArticle
Sensors 2011, 11(6), 5968-5980;

Cytochrome C Biosensor—A Model for Gas Sensing

Sony Deutschland GmbH, Materials Science Laboratory, Hedelfinger Strasse 61, 70327 Stuttgart, Germany
Author to whom correspondence should be addressed.
Received: 14 April 2011 / Accepted: 23 May 2011 / Published: 1 June 2011
(This article belongs to the Special Issue Bioinspired Sensor Systems)
Full-Text   |   PDF [436 KB, uploaded 21 June 2014]   |  


This work is about gas biosensing with a cytochrome c biosensor. Emphasis is put on the analysis of the sensing process and a mathematical model to make predictions about the biosensor response. Reliable predictions about biosensor responses can provide valuable information and facilitate biosensor development, particularly at an early development stage. The sensing process comprises several individual steps, such as phase partition equilibrium, intermediate reactions, mass-transport, and reaction kinetics, which take place in and between the gas and liquid phases. A quantitative description of each step was worked out and finally combined into a mathematical model. The applicability of the model was demonstrated for a particular example of methanethiol gas detection by a cytochrome c biosensor. The model allowed us to predict the optical readout response of the biosensor from tabulated data and data obtained in simple liquid phase experiments. The prediction was experimentally verified with a planar three-electrode electro-optical cytochrome c biosensor in contact with methanethiol gas in a gas tight spectroelectrochemical measurement cell. View Full-Text
Keywords: cytochrome c; biosensor; thiol; prediction; model; sensing process cytochrome c; biosensor; thiol; prediction; model; sensing process

Graphical abstract

This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Share & Cite This Article

MDPI and ACS Style

Hulko, M.; Hospach, I.; Krasteva, N.; Nelles, G. Cytochrome C Biosensor—A Model for Gas Sensing. Sensors 2011, 11, 5968-5980.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics



[Return to top]
Sensors EISSN 1424-8220 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top