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Synthesis, Crystal Structure and Cyclic Voltammetric Behavior of N-aroyl-N′-(4′-cyanophenyl)thioureas
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N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky Prospekt, 119991 Moscow, Russia
Author to whom correspondence should be addressed.
Academic Editor: Nicholas E. Leadbeater
Molbank 2022, 2022(1), M1317;
Received: 30 December 2021 / Revised: 11 January 2022 / Accepted: 12 January 2022 / Published: 14 January 2022
Michael addition–halogenation–intramolecular ring-closing (MHIRC) reactions are processes in which a halogen atom as a leaving group can attach to substrates or reactants during the reaction, which then undergoes intramolecular ring closure. In this communication the MHIRC transformation of 4-benzylidene-3-phenylisoxazol-5(4H)-one and 1,3-dimethylbarbituric acid in the presence of N-bromosuccinimide and sodium acetate in EtOH at room temperature was carefully investigated to give novel 1,3-dimethyl-3′,5-diphenyl-1,5-dihydro-2H,5′H-spiro[furo[2,3-d]pyrimi- dine-6,4′-isoxazole]-2,4,5′(3H)-trione in a good yield. The structure of the new compound was confirmed by the results of elemental analysis as well as mass, nuclear magnetic resonance, and infrared spectroscopy. View Full-Text
Keywords: 4-benzylidene-3-phenylisoxazol-5(4H)-one; 1,3-dimethylbarbituric acid; spiro[furo[2,3-d]pyrimidine]; N-bromosuccinimide; MHIRC process 4-benzylidene-3-phenylisoxazol-5(4H)-one; 1,3-dimethylbarbituric acid; spiro[furo[2,3-d]pyrimidine]; N-bromosuccinimide; MHIRC process
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MDPI and ACS Style

Ryzhkova, Y.E.; Kalashnikova, V.M.; Ryzhkov, F.V.; Elinson, M.N. 1,3-Dimethyl-3′,5-diphenyl-1,5-dihydro-2H,5′H-spiro[furo[2,3-d]pyrimidine-6,4′-isoxazole]-2,4,5′(3H)-trione. Molbank 2022, 2022, M1317.

AMA Style

Ryzhkova YE, Kalashnikova VM, Ryzhkov FV, Elinson MN. 1,3-Dimethyl-3′,5-diphenyl-1,5-dihydro-2H,5′H-spiro[furo[2,3-d]pyrimidine-6,4′-isoxazole]-2,4,5′(3H)-trione. Molbank. 2022; 2022(1):M1317.

Chicago/Turabian Style

Ryzhkova, Yuliya E., Varvara M. Kalashnikova, Fedor V. Ryzhkov, and Michail N. Elinson. 2022. "1,3-Dimethyl-3′,5-diphenyl-1,5-dihydro-2H,5′H-spiro[furo[2,3-d]pyrimidine-6,4′-isoxazole]-2,4,5′(3H)-trione" Molbank 2022, no. 1: M1317.

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