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Open AccessShort Note

N-(2-(1H-indol-3-yl)ethyl)-2-(2-fluoro-[1,1′-biphenyl]-4-yl)propanamide

1
Department of Organic Chemistry, Faculty of Chemistry, University of Plovdiv, 24 Tzar Assen Str., 4000 Plovdiv, Bulgaria
2
Department of Natural-Mathematical and Business Sciences, University of Plovdiv, Branch Smolyan, 32 “Dicho Petrov” Str., 4700 Smolyan, Bulgaria
*
Author to whom correspondence should be addressed.
Academic Editor: René T. Boeré
Molbank 2021, 2021(1), M1177; https://doi.org/10.3390/M1177
Received: 4 December 2020 / Revised: 29 December 2020 / Accepted: 30 December 2020 / Published: 31 December 2020
(This article belongs to the Section Structure Determination)
N-(2-(1H-Indol-3-yl)ethyl)-2-(2-fluoro-[1,1′-biphenyl]-4-yl)propanamide was prepared by a reaction between tryptamine and flurbiprofen, applying N,N’-dicyclohexylcarbodiimide, as a coupling agent. The obtained new amide has a fragment similar to Brequinar, a compound used in SARS-CoV-2 treatment trials. The newly synthesized compound was fully analyzed and characterized via 1H, 13C-NMR, UV, IR, and mass spectral data. View Full-Text
Keywords: amide; flurbiprofen; SARS-CoV-2; tryptamine amide; flurbiprofen; SARS-CoV-2; tryptamine
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MDPI and ACS Style

Manolov, S.; Ivanov, I.; Bojilov, D. N-(2-(1H-indol-3-yl)ethyl)-2-(2-fluoro-[1,1′-biphenyl]-4-yl)propanamide. Molbank 2021, 2021, M1177.

AMA Style

Manolov S, Ivanov I, Bojilov D. N-(2-(1H-indol-3-yl)ethyl)-2-(2-fluoro-[1,1′-biphenyl]-4-yl)propanamide. Molbank. 2021; 2021(1):M1177.

Chicago/Turabian Style

Manolov, Stanimir; Ivanov, Iliyan; Bojilov, Dimitar. 2021. "N-(2-(1H-indol-3-yl)ethyl)-2-(2-fluoro-[1,1′-biphenyl]-4-yl)propanamide" Molbank 2021, no. 1: M1177.

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