Review Reports
- Sung Jun Hong1,2,†,
- Minsung Bock3,† and
- Songzi Zhang3
- et al.
Reviewer 1: Andrea Capucciati Reviewer 2: Anonymous
Round 1
Reviewer 1 Report
Comments and Suggestions for AuthorsIn this review, the authors highlight the fact that many treatments for damage to the central nervous system are not available today. Many of these damages can lead to irreversible neurological deficiencies. The review highlights the potential role of organoids in direct repair at injury sites. In particular, the authors critically analyze and evaluate preclinical transplantation results, advantages and disadvantages. The use of organoids could be used in the future to study the phenomenon of neuro-regeneration.
The review is well written and clear; the topic is of great interest to the scientific community, especially of great interest for the study of neurodegenerative diseases.
The figures are clear and very understandable. The literature references are complete and relevant.
Section 3.3 Parkinson's Disease lacks a brief reference to the hallmarks of the disease: the role of synuclein (aggregation) and neuromelanin.
The review deserves publication after the suggested addition of a small reference to the hallmarks of Parkinson's disease
Author Response
Please see the attachment.
Author Response File: 
Author Response.pdf
Reviewer 2 Report
Comments and Suggestions for AuthorsPlease see attached document
Comments for author File: Comments.pdf
Minor editing of English language required
Author Response
Please see the attachment.
Author Response File: Author Response.pdf