Ion Channel Partnerships: Odd and Not-So-Odd Couples Controlling Neuronal Ion Channel Function
Abstract
:1. Introduction
2. Canonical Ion Channel Partnerships
2.1. PM-ER Ion Channel Partnerships
2.2. Cav1-RyR
2.3. VGCC–RyR–KCa
2.4. VGCC–BK
2.5. VGCC–IK
3. Non-Canonical Ion Channel Partnerships
3.1. VGCC–Kv Channel Partnerships
3.1.1. Cav3–Kv4
3.1.2. Cav2.3–Kv4.2
3.2. Ion Channel Partnerships Involving Non-Conducting Functions of Ion Channels
Cav1.2–Kv2.1
4. Restricted Subcellular Compartmentalization of Ion Channel Partnerships
5. Conclusions and Future Perspectives
Author Contributions
Funding
Conflicts of Interest
References
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Cav α1 Subunit | Ca2+ Current |
---|---|
Cav1.1 | L-type |
Cav1.2 | L-type |
Cav1.3 | L-type |
Cav1.4 | L-type |
Cav2.1 | P/Q-type |
Cav2.2 | N-type |
Cav2.3 | R-type |
Cav3.1 | T-type |
Cav3.2 | T-type |
Cav3.3 | T-type |
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Vierra, N.C.; Trimmer, J.S. Ion Channel Partnerships: Odd and Not-So-Odd Couples Controlling Neuronal Ion Channel Function. Int. J. Mol. Sci. 2022, 23, 1953. https://doi.org/10.3390/ijms23041953
Vierra NC, Trimmer JS. Ion Channel Partnerships: Odd and Not-So-Odd Couples Controlling Neuronal Ion Channel Function. International Journal of Molecular Sciences. 2022; 23(4):1953. https://doi.org/10.3390/ijms23041953
Chicago/Turabian StyleVierra, Nicholas C., and James S. Trimmer. 2022. "Ion Channel Partnerships: Odd and Not-So-Odd Couples Controlling Neuronal Ion Channel Function" International Journal of Molecular Sciences 23, no. 4: 1953. https://doi.org/10.3390/ijms23041953