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Review

Associations between Adipokines in Arthritic Disease and Implications for Obesity

1
Graduate Institute of Basic Medical Science, China Medical University, Taichung 40402, Taiwan
2
Department of Orthopedic Surgery, China Medical University Hospital, Taichung 40447, Taiwan
3
Graduate Institute of Clinical Medical Science, China Medical University, Taichung 40447, Taiwan
4
Division of Immunology and Rheumatology, Department of Internal Medicine, China Medical University Hospital, Taichung 40447, Taiwan
5
Department of Anatomy, China Medical University, Taichung 40402, Taiwan
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School of Medicine, China Medical University, Taichung 40402, Taiwan
7
Chinese Medicine Research Center, China Medical University, Taichung 40447, Taiwan
8
Department of Biotechnology, College of Health Science, Asia University, Taichung 41354, Taiwan
*
Author to whom correspondence should be addressed.
Int. J. Mol. Sci. 2019, 20(6), 1505; https://doi.org/10.3390/ijms20061505
Received: 4 March 2019 / Revised: 18 March 2019 / Accepted: 21 March 2019 / Published: 26 March 2019
(This article belongs to the Special Issue Research of Pathogenesis and Novel Therapeutics in Arthritis)
Secretion from adipose tissue of adipokines or adipocytokines, comprising of bioactive peptides or proteins, immune molecules and inflammatory mediators, exert critical roles in inflammatory arthritis and obesity. This review considers the evidence generated over the last decade regarding the effects of several adipokines including leptin, adiponectin, visfatin, resistin, chemerin and apelin, in cartilage and bone homeostasis in the pathogenesis of rheumatoid arthritis and osteoarthritis, which has important implications for obesity. View Full-Text
Keywords: rheumatoid arthritis; osteoarthritis; adipokines; obesity rheumatoid arthritis; osteoarthritis; adipokines; obesity
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MDPI and ACS Style

MᵃᶜDonald, I.J.; Liu, S.-C.; Huang, C.-C.; Kuo, S.-J.; Tsai, C.-H.; Tang, C.-H. Associations between Adipokines in Arthritic Disease and Implications for Obesity. Int. J. Mol. Sci. 2019, 20, 1505. https://doi.org/10.3390/ijms20061505

AMA Style

MᵃᶜDonald IJ, Liu S-C, Huang C-C, Kuo S-J, Tsai C-H, Tang C-H. Associations between Adipokines in Arthritic Disease and Implications for Obesity. International Journal of Molecular Sciences. 2019; 20(6):1505. https://doi.org/10.3390/ijms20061505

Chicago/Turabian Style

MᵃᶜDonald, Iona J., Shan-Chi Liu, Chien-Chung Huang, Shu-Jui Kuo, Chun-Hao Tsai, and Chih-Hsin Tang. 2019. "Associations between Adipokines in Arthritic Disease and Implications for Obesity" International Journal of Molecular Sciences 20, no. 6: 1505. https://doi.org/10.3390/ijms20061505

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