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Review

A MicroRNA Perspective on Cardiovascular Development and Diseases: An Update

Tecnologico de Monterrey, Grupo de Investigación con Enfoque Estratégico en Bioingeniería y Medicina Regenerativa, Escuela de Medicina y Ciencias de la Salud, Ave. Morones Prieto 3000, Monterrey, NL 64710, Mexico
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Int. J. Mol. Sci. 2018, 19(7), 2075; https://doi.org/10.3390/ijms19072075
Received: 8 May 2018 / Revised: 2 July 2018 / Accepted: 10 July 2018 / Published: 17 July 2018
(This article belongs to the Section Biochemistry)
In this review, we summarize the latest research pertaining to MicroRNAs (miRs) related to cardiovascular diseases. In today’s molecular age, the key clinical aspects of diagnosing and treating these type of diseases are crucial, and miRs play an important role. Therefore, we have made a thorough analysis discussing the most important candidate protagonists of many pathways relating to such conditions as atherosclerosis, heart failure, myocardial infarction, and congenital heart disorders. We approach miRs initially from the fundamental molecular aspects and look at their role in developmental pathways, as well as regulatory mechanisms dysregulated under specific cardiovascular conditions. By doing so, we can better understand their functional roles. Next, we look at therapeutic aspects, including delivery and inhibition techniques. We conclude that a personal approach for treatment is paramount, and so understanding miRs is strategic for cardiovascular health. View Full-Text
Keywords: microRNA; cardiovascular diseases; myocardial infarction; atherosclerosis; heart failure microRNA; cardiovascular diseases; myocardial infarction; atherosclerosis; heart failure
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MDPI and ACS Style

Islas, J.F.; Moreno-Cuevas, J.E. A MicroRNA Perspective on Cardiovascular Development and Diseases: An Update. Int. J. Mol. Sci. 2018, 19, 2075. https://doi.org/10.3390/ijms19072075

AMA Style

Islas JF, Moreno-Cuevas JE. A MicroRNA Perspective on Cardiovascular Development and Diseases: An Update. International Journal of Molecular Sciences. 2018; 19(7):2075. https://doi.org/10.3390/ijms19072075

Chicago/Turabian Style

Islas, Jose F., and Jorge E. Moreno-Cuevas 2018. "A MicroRNA Perspective on Cardiovascular Development and Diseases: An Update" International Journal of Molecular Sciences 19, no. 7: 2075. https://doi.org/10.3390/ijms19072075

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