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Int. J. Mol. Sci. 2017, 18(6), 1242;

Legume Lectins: Proteins with Diverse Applications

CONACyT-Universidad de Sonora, Blvd. Luis Encinas y Rosales, Hermosillo, Sonora 83000, Mexico
Coordinacion de Ciencia de los Alimentos, Centro de Investigacion en Alimentacion y Desarrollo, A.C., Apartado Postal 1735, Hermosillo, Sonora 83304, Mexico
Author to whom correspondence should be addressed.
Academic Editor: Els Van Damme
Received: 29 April 2017 / Revised: 1 June 2017 / Accepted: 5 June 2017 / Published: 12 June 2017
(This article belongs to the Special Issue Plant Lectins: From Model Species to Crop Plants)
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Lectins are a diverse class of proteins distributed extensively in nature. Among these proteins; legume lectins display a variety of interesting features including antimicrobial; insecticidal and antitumor activities. Because lectins recognize and bind to specific glycoconjugates present on the surface of cells and intracellular structures; they can serve as potential target molecules for developing practical applications in the fields of food; agriculture; health and pharmaceutical research. This review presents the current knowledge of the main structural characteristics of legume lectins and the relationship of structure to the exhibited specificities; provides an overview of their particular antimicrobial; insecticidal and antitumor biological activities and describes possible applications based on the pattern of recognized glyco-targets. View Full-Text
Keywords: lectin; legume; insecticidal; antimicrobial; cancer lectin; legume; insecticidal; antimicrobial; cancer

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Lagarda-Diaz, I.; Guzman-Partida, A.M.; Vazquez-Moreno, L. Legume Lectins: Proteins with Diverse Applications. Int. J. Mol. Sci. 2017, 18, 1242.

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