Convenient Replacement of the Hydroxy by an Amino Group in 4 Hydroxycoumarin and 4-Hydroxy-6-methyl-2-pyrone under Microwave Irradiation
Abstract
:Introduction
Results and Discussion
Starting compounds | Reaction time a (min) | Product | M.p., °C | Yield, % |
1 + butylamine (2a) | 2.0 | 3a | 117-119 [3] | 90 |
1 + pentylamine (2b) | 2.0 | 3b | 162-164 [3] | 83 |
1 + cyclohexylamine (2c) | 2.0 | 3c | 193-195 [3] | 40 |
1 + aniline (2d) | 2.0 | 3d | 267-268 [4] | 97 |
1 + benzylamine (2e) | 2.0 | 3e | 240-242 [4] | 98 |
1 + phenethylamine (2f) | 2.0 | 3f | 169-171 [4] | 97 |
1 + 1-phenylethylamine (2g) | 2.0 | 3g | 186-187 | 95 |
1 + 3-phenylpropylamine (2h) | 2.0 | 3h | 167-169 | 94 |
1 + morpholine (2i) | 1.5 | 3i | 140-141 [5] | 73 |
4 + benzylamine (2e) | 10 | 5e | 185-187 [7,8] | 90 |
4 + phenethylamine (2f) | 10 | 5f | 166-168 [7,8] | 93 |
Conclusions
Experimental
General procedure
Spectral Data
References and Notes
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- Samples Availability: Available from the authors.
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Stoyanov, E.V.; Ivanov, I.C. Convenient Replacement of the Hydroxy by an Amino Group in 4 Hydroxycoumarin and 4-Hydroxy-6-methyl-2-pyrone under Microwave Irradiation. Molecules 2004, 9, 627-631. https://doi.org/10.3390/90800627
Stoyanov EV, Ivanov IC. Convenient Replacement of the Hydroxy by an Amino Group in 4 Hydroxycoumarin and 4-Hydroxy-6-methyl-2-pyrone under Microwave Irradiation. Molecules. 2004; 9(8):627-631. https://doi.org/10.3390/90800627
Chicago/Turabian StyleStoyanov, Edmont V., and Ivo C. Ivanov. 2004. "Convenient Replacement of the Hydroxy by an Amino Group in 4 Hydroxycoumarin and 4-Hydroxy-6-methyl-2-pyrone under Microwave Irradiation" Molecules 9, no. 8: 627-631. https://doi.org/10.3390/90800627