Synthesis and Catalytic Activity of Two New Cyclic Tetraaza Ligands
Abstract
:Introduction
Results and Discussion
Catalysis
Experimental
General
Synthesis of the ligands
References and Notes
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- A sample of 7.041 mg of 3 was heated under N2 from 25 to 300 °C at a rate of 10 °C/min. The reaction set in at 259.1 °C and the sample lost 0.818 mg in weight, which corresponds to the loss of CO2 (theoretically 0.794 mg).
- The preparative synthesis of 4 thus never succeeded. Possible alternate ways of obtaining this compound could be to react the tetraaza ligand 1 with urea while heating (Davis, T. L.; Underwood, H. W., Jr. J. Am. Chem. Soc. 1922, 44, 2595–2604.), with phosgene in benzene (Jones, L. W.; Root, F. B. J. Am. Chem. Soc. 1926, 48, 181–195.), with diphosgene in dioxane (Cordier, D.; Coulet, P. R. J. Chem. Soc. Perkin Trans. 2 1994, 4, 891–894.) or with carbon dioxide in the presence of a strong base or with methyl chloroformate and Et3N in CH2Cl2 (Naito, R.; Takeuchi, M.; Morihira, K.; Hayakawa, M.; Ikeda, K.; Shibanuma, T.; Isomura, Y. Chem. Pharm. Bull. 1998, 43, 1286–1294.).
- While with ligand 2 the racemic alcohol was obtained, ligand 3 gave the R-isomer in 6 % ee.
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- Sample availability: Samples of compounds 1, 2 and 3 are available from MDPI.
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Fonseca, M.H.; Hjelmgaard, T.; König, B. Synthesis and Catalytic Activity of Two New Cyclic Tetraaza Ligands. Molecules 2003, 8, 453-458. https://doi.org/10.3390/80500453
Fonseca MH, Hjelmgaard T, König B. Synthesis and Catalytic Activity of Two New Cyclic Tetraaza Ligands. Molecules. 2003; 8(5):453-458. https://doi.org/10.3390/80500453
Chicago/Turabian StyleFonseca, María Hechavarría, Thomas Hjelmgaard, and Burkhard König. 2003. "Synthesis and Catalytic Activity of Two New Cyclic Tetraaza Ligands" Molecules 8, no. 5: 453-458. https://doi.org/10.3390/80500453