Gastric Cytoprotective Activity of Ilicic Aldehyde in Rats and Mice
Abstract
:Introduction
Material and Methods
Oxidation
Pharmacological assays
Results and discussion
- In the first experiment: L. 1: 4,80 ± 0,27; L. 2: 4,37 ± 0,25; L. 3: 4,33 ± 0,57; L. 4: 1,50 ± 0,50*; L. 5: 0,83 ± 0,28*; L. 6: 0,75 ± 0,28** (*p<0,00001; **p<0,0001 vs. controls. Each value represents the mean ± SEM).
- In the experiment performed to study whether 2 protects the gastric mucosa in rats at different doses: 25 mM: 1,5 ± 0,11; 50 mM: 1,08 ± 0,12; 75 mM: 0,6 ± 0,11; 100 mM: 0,20 ± 0,10. ED50 = 21,57 ± 4,22 mM.
- In the evaluation of gastroprotective activity in mice: L. control: 4,75 ± 0,15; L. 0,43 ± 0,11* (91% of cytoprotection) ( *p<0,00001 vs. control).
Acknowledgements
References and Notes
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Share and Cite
Donadel, O.J.; María, A.; Wendel, G.; Guerreiro, E.; Giordano, O. Gastric Cytoprotective Activity of Ilicic Aldehyde in Rats and Mice. Molecules 2000, 5, 462-464. https://doi.org/10.3390/50300462
Donadel OJ, María A, Wendel G, Guerreiro E, Giordano O. Gastric Cytoprotective Activity of Ilicic Aldehyde in Rats and Mice. Molecules. 2000; 5(3):462-464. https://doi.org/10.3390/50300462
Chicago/Turabian StyleDonadel, O. J., A. María, G. Wendel, E. Guerreiro, and O. Giordano. 2000. "Gastric Cytoprotective Activity of Ilicic Aldehyde in Rats and Mice" Molecules 5, no. 3: 462-464. https://doi.org/10.3390/50300462