Fabrication and Properties of the Multifunctional Rapid Wound Healing Panax notoginseng@Ag Electrospun Fiber Membrane
Abstract
:1. Introduction
2. Results and Discussion
2.1. Characterization of the PN@8 wt%Ag-2 h Core/Shell Fiber Membrane
2.2. The Swelling Ratio of Prepared Nanofiber Membranes
2.3. Antibacterial Results of the PN@Ag Electrospun Nanofiber Membrane
2.4. Cytotoxicity of Electrospun Nanofiber Membranes
2.5. In Vivo Wound Healing in Sprague Dawley Mice
3. Experimental Section
3.1. Materials
3.2. Preparation of Electrospun Fiber Membranes
3.3. Characterizations
3.4. Antibacterial Evaluation Assay
3.5. Cytotoxicity of Electrospun Nanofiber Membrane
3.6. Establishment of Wounds in Mice and Wound Healing In Vivo
4. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
Sample Availability
References
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Weight before Moisture Absorption M0 (g) | Weight After Moisture Absorption M1 (g) | Difference Value ΔM (g) | Swelling Ratio (%) | Average Swelling Ratio (%) |
---|---|---|---|---|
0.029 | 0.045 | 0.016 | 55.17 | 57.74 |
0.030 | 0.048 | 0.018 | 60.00 | |
0.031 | 0.049 | 0.018 | 58.06 |
Weight before Moisture Absorption M0 (g) | Weight after Moisture Absorption M1 (g) | Difference Value ΔM (g) | Swelling Ratio (%) | Average Swelling Ratio (%) |
---|---|---|---|---|
0.029 | 0.087 | 0.058 | 200.0 | 199.87 |
0.030 | 0.087 | 0.057 | 190.0 | |
0.031 | 0.096 | 0.065 | 209.6 |
PN in the Electrospun Core Solution (g) | AgNO3 in the Electrospun Shell Solution (g) | The Mass of CS in the Electrospun Core Solution (g) | The Irradiation Time of 254 nm Ultraviolet (h) | Sample Name |
---|---|---|---|---|
0.08 | 0.12 | 0.12 | 2 | PN@8 wt%Ag-2 h |
0.08 | 0 | 0.12 | 0 | PCL@PN |
0 | 0.12 | 0.12 | 2 | PVP@Ag |
0.08 | 0.09 | 0.12 | 2 | PN@6 wt%Ag-2 h |
0.08 | 0.15 | 0.12 | 2 | PN@10 wt%Ag-2 h |
0.08 | 0.12 | 0 | 2 | PN@8 wt%Ag-NCS |
0 | 0 | 0.12 | 0 | Blank membrane |
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Gao, Z.; Liu, S.; Li, S.; Shao, X.; Zhang, P.; Yao, Q. Fabrication and Properties of the Multifunctional Rapid Wound Healing Panax notoginseng@Ag Electrospun Fiber Membrane. Molecules 2023, 28, 2972. https://doi.org/10.3390/molecules28072972
Gao Z, Liu S, Li S, Shao X, Zhang P, Yao Q. Fabrication and Properties of the Multifunctional Rapid Wound Healing Panax notoginseng@Ag Electrospun Fiber Membrane. Molecules. 2023; 28(7):2972. https://doi.org/10.3390/molecules28072972
Chicago/Turabian StyleGao, Zhaoju, Songlin Liu, Shangfei Li, Xinzhe Shao, Pingping Zhang, and Qingqiang Yao. 2023. "Fabrication and Properties of the Multifunctional Rapid Wound Healing Panax notoginseng@Ag Electrospun Fiber Membrane" Molecules 28, no. 7: 2972. https://doi.org/10.3390/molecules28072972