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Article

Visible-Light-Induced, Graphene Oxide-Promoted C3-Chalcogenylation of Indoles Strategy under Transition-Metal-Free Conditions

1
Department of Chemistry and Chemical Engineering, Gannan Normal University, Ganzhou 341000, China
2
Key Laboratory of Prevention and Treatment of Cardiovascular and Cerebrovascular Diseases of Ministry of Education, School of Pharmaceutical Science of Gannan Medical University, Ganzhou 341000, China
*
Authors to whom correspondence should be addressed.
Academic Editor: Barbara Morzyk-Ociepa
Molecules 2022, 27(3), 772; https://doi.org/10.3390/molecules27030772
Received: 14 December 2021 / Revised: 16 January 2022 / Accepted: 19 January 2022 / Published: 25 January 2022
An efficient and general method for the synthesis of 3-sulfenylindoles and 3-selenylindoles employing visible-light irradiation with graphene oxide as a promoter at room temperature has been achieved. The reaction features are high yields, simple operation, metal-free and iodine-free conditions, an easy-to-handle oxidant, and gram-scalable synthesis. This simple protocol allows one to access a wide range of 3-arylthioindoles, 3-arylselenylindoles, and even 3-thiocyanatoindoles with good to excellent yields. View Full-Text
Keywords: graphene oxide; visible-light; indole; sulfenylindole; selenylindole graphene oxide; visible-light; indole; sulfenylindole; selenylindole
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MDPI and ACS Style

Huang, Q.; Peng, X.; Li, H.; He, H.; Liu, L. Visible-Light-Induced, Graphene Oxide-Promoted C3-Chalcogenylation of Indoles Strategy under Transition-Metal-Free Conditions. Molecules 2022, 27, 772. https://doi.org/10.3390/molecules27030772

AMA Style

Huang Q, Peng X, Li H, He H, Liu L. Visible-Light-Induced, Graphene Oxide-Promoted C3-Chalcogenylation of Indoles Strategy under Transition-Metal-Free Conditions. Molecules. 2022; 27(3):772. https://doi.org/10.3390/molecules27030772

Chicago/Turabian Style

Huang, Qing, Xiangjun Peng, Hong Li, Haiping He, and Liangxian Liu. 2022. "Visible-Light-Induced, Graphene Oxide-Promoted C3-Chalcogenylation of Indoles Strategy under Transition-Metal-Free Conditions" Molecules 27, no. 3: 772. https://doi.org/10.3390/molecules27030772

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