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Review

The Role of Hydrogen Bond Donor on the Extraction of Phenolic Compounds from Natural Matrices Using Deep Eutectic Systems

1
LAQV, REQUIMTE, Departamento de Química da Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa, 2829-516 Caparica, Portugal
2
Des Solutio, Avenida Tenente Valadim, nº 17, 2ºF, 2560-275 Torres Vedras, Portugal
*
Author to whom correspondence should be addressed.
Academic Editor: Matteo Guidotti
Molecules 2021, 26(8), 2336; https://doi.org/10.3390/molecules26082336
Received: 18 March 2021 / Revised: 12 April 2021 / Accepted: 13 April 2021 / Published: 17 April 2021
(This article belongs to the Special Issue Review Papers in Green Chemistry)
Recently, deep eutectic systems (DESs) as extraction techniques for bioactive compounds have surfaced as a greener alternative to common organic solvents. In order to study the effect of these systems on the extraction of phenolic compounds from different natural sources, a comprehensive review of the state of the art was carried out. In a first approach, the addition of water to these systems and its effect on DES physicochemical properties such as polarity, viscosity, and acidity was investigated. This review studied the effect of the hydrogen bond donor (HBD) on the nature of the extracted phenolics. The effects of the nature of the HBD, namely carbon chain length as well as the number of hydroxyl, methyl, and carbonyl groups, have shown to play a critical role in the extraction of different phenolic compounds. This review highlights the differences between DES systems and systematizes the results published in the literature, so that a more comprehensive evaluation of the systems can be carried out before any experimental trial. View Full-Text
Keywords: deep eutectic systems; phenolic compounds; antioxidants; natural matrices; hydrogen bond donor; extraction deep eutectic systems; phenolic compounds; antioxidants; natural matrices; hydrogen bond donor; extraction
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MDPI and ACS Style

Rente, D.; Paiva, A.; Duarte, A.R. The Role of Hydrogen Bond Donor on the Extraction of Phenolic Compounds from Natural Matrices Using Deep Eutectic Systems. Molecules 2021, 26, 2336. https://doi.org/10.3390/molecules26082336

AMA Style

Rente D, Paiva A, Duarte AR. The Role of Hydrogen Bond Donor on the Extraction of Phenolic Compounds from Natural Matrices Using Deep Eutectic Systems. Molecules. 2021; 26(8):2336. https://doi.org/10.3390/molecules26082336

Chicago/Turabian Style

Rente, Duarte, Alexandre Paiva, and Ana R. Duarte 2021. "The Role of Hydrogen Bond Donor on the Extraction of Phenolic Compounds from Natural Matrices Using Deep Eutectic Systems" Molecules 26, no. 8: 2336. https://doi.org/10.3390/molecules26082336

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