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Review

Herbal Products Used in Menopause and for Gynecological Disorders

by
Maša Kenda
1,
Nina Kočevar Glavač
1,
Milan Nagy
2,
Marija Sollner Dolenc
1,* and
on behalf of the OEMONOM
†
1
University of Ljubljana, Faculty of Pharmacy, Aškerčeva Cesta 7, 1000 Ljubljana, Slovenia
2
Comenius University in Bratislava, Faculty of Pharmacy, 83232 Bratislava, Slovakia
*
Author to whom correspondence should be addressed.
†
Listed at the end of Acknowledgments.
Molecules 2021, 26(24), 7421; https://doi.org/10.3390/molecules26247421
Submission received: 31 October 2021 / Revised: 29 November 2021 / Accepted: 2 December 2021 / Published: 8 December 2021
(This article belongs to the Special Issue The Pharmacological Properties and Therapeutic Use of Natural Products)
Review Reports Versions Notes

Abstract

Herbal products are often used as an alternative to pharmacological therapy. Menopausal symptoms and gynecological disorders (such as premenstrual syndrome and dysmenorrhea) are the indications where pharmacological therapy may have serious adverse events, hence many women prefer to use herbal products to help with these symptoms. Here, we reviewed plants and derived products, which are commonly used for the abovementioned indications, focusing on clinical data, safely profile and whether or not their use is justified. We noted that limited data are available on the use of some plants for alleviating the symptoms of menopause and gynecological disorders. While black cohosh (Cimicifuga racemose) and red clover (Trifolium pretense) were consistently shown to help reduce menopausal symptoms in clinical studies, currently available data do not fully support the use of fenugreek (Trigonella foenum-graecum), hops (Humulus lupulus), valerian (Valeriana officinalis), and soybean (Glycine max and Glycine soja) for this indication. For premenstrual syndrome and premenstrual dysphoric disorder, chaste tree (Vitex agnus-castus) shows effectiveness, but more clinical studies are needed to confirm such effect upon the use of evening primrose (Oenothera biennis).
Keywords: menopause; dysmenorrhea; premenstrual syndrome; gynecological disorders; herbal products; medicinal plants menopause; dysmenorrhea; premenstrual syndrome; gynecological disorders; herbal products; medicinal plants

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MDPI and ACS Style

Kenda, M.; Glavač, N.K.; Nagy, M.; Sollner Dolenc, M.; on behalf of the OEMONOM. Herbal Products Used in Menopause and for Gynecological Disorders. Molecules 2021, 26, 7421. https://doi.org/10.3390/molecules26247421

AMA Style

Kenda M, Glavač NK, Nagy M, Sollner Dolenc M, on behalf of the OEMONOM. Herbal Products Used in Menopause and for Gynecological Disorders. Molecules. 2021; 26(24):7421. https://doi.org/10.3390/molecules26247421

Chicago/Turabian Style

Kenda, Maša, Nina Kočevar Glavač, Milan Nagy, Marija Sollner Dolenc, and on behalf of the OEMONOM. 2021. "Herbal Products Used in Menopause and for Gynecological Disorders" Molecules 26, no. 24: 7421. https://doi.org/10.3390/molecules26247421

APA Style

Kenda, M., Glavač, N. K., Nagy, M., Sollner Dolenc, M., & on behalf of the OEMONOM. (2021). Herbal Products Used in Menopause and for Gynecological Disorders. Molecules, 26(24), 7421. https://doi.org/10.3390/molecules26247421

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