Lead Levels in Non-Occupationally Exposed Women with Preeclampsia
1
Department of Analytical Chemistry, Medical University of Lublin, Chodźki 4a Street, 20-093 Lublin, Poland
2
Department of Obstetrics and Perinatology, Medical University of Lublin, Jaczewskiego 8 Street, 20-090 Lublin, Poland
3
LAQV/REQUIMTE, Laboratory of Applied Chemistry, Department of Chemical Sciences, Faculty of Pharmacy, University of Porto, 4050-313 Porto, Portugal
4
Department of Environmental Health, School of Health, P. Porto, R. Dr. António Bernardino de Almeida 400, 4200-072 Porto, Portugal
5
Department of Human Physiology, Medical University of Lublin, Radziwiłłowska 11 Street, 20-080 Lublin, Poland
*
Author to whom correspondence should be addressed.
Academic Editor: Yannis Dotsikas
Molecules 2021, 26(10), 3051; https://doi.org/10.3390/molecules26103051
Received: 31 March 2021
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Revised: 15 May 2021
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Accepted: 17 May 2021
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Published: 20 May 2021
There are many controversies regarding the relationship between lead exposure andcomplications in pregnancy. Preeclampsia (PE) is a maternal hypertensive disorder which is one of the main causes of maternal and foetal mortality. The aim of our study was to assess blood lead level (BLL) in Polish women with PE (PE group, n = 66) compared with healthy, non-pregnant women (CNP group, n = 40) and healthy pregnant women (CP group, n = 40). BLL was determined by inductively coupled plasma mass spectrometry (ICP-MS). The systolic blood pressure (SBP), diastolic blood pressure (DBP) and BLL in the CP group were significantly lower than in the PE group (p < 0.001). Logistic regression analyses of BLL showed a significant positive relationship with the presence of PE. Furthermore, both the SBP and DBP values were positively associated with BLL. This study indicates that preeclamptic women tend to present with significantly higher BLL compared to healthy pregnant women. There were no differences in the BLL between the CP and CNP groups.
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Keywords:
lead; preeclampsia; pregnancy; blood pressure
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MDPI and ACS Style
Gajewska, K.; Laskowska, M.; Almeida, A.; Pinto, E.; Skórzyńska-Dziduszko, K.; Błażewicz, A. Lead Levels in Non-Occupationally Exposed Women with Preeclampsia. Molecules 2021, 26, 3051. https://doi.org/10.3390/molecules26103051
AMA Style
Gajewska K, Laskowska M, Almeida A, Pinto E, Skórzyńska-Dziduszko K, Błażewicz A. Lead Levels in Non-Occupationally Exposed Women with Preeclampsia. Molecules. 2021; 26(10):3051. https://doi.org/10.3390/molecules26103051
Chicago/Turabian StyleGajewska, Katarzyna, Marzena Laskowska, Agostinho Almeida, Edgar Pinto, Katarzyna Skórzyńska-Dziduszko, and Anna Błażewicz. 2021. "Lead Levels in Non-Occupationally Exposed Women with Preeclampsia" Molecules 26, no. 10: 3051. https://doi.org/10.3390/molecules26103051
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