Next Article in Journal
Effect of the Immobilization Strategy on the Efficiency and Recyclability of the Versatile Lipase from Ophiostoma piceae
Next Article in Special Issue
A Sample Preparation Technique Using Biocompatible Composites for Biomedical Applications
Previous Article in Journal
Discovery of Novel Triazole-Containing Pyrazole Ester Derivatives as Potential Antibacterial Agents
Previous Article in Special Issue
A Vortex-Assisted Dispersive Liquid-Liquid Microextraction Followed by UPLC-MS/MS for Simultaneous Determination of Pesticides and Aflatoxins in Herbal Tea
Article Menu
Issue 7 (April-1) cover image

Export Article

Open AccessArticle

New Vortex-Synchronized Matrix Solid-Phase Dispersion Method for Simultaneous Determination of Four Anthraquinones in Cassiae Semen

1,†, 2,†, 1, 1, 2,* and 1,*
1
College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou 310014, China
2
College of Materials Science and Engineering, Zhejiang University of Technology, Hangzhou 310014, China
*
Authors to whom correspondence should be addressed.
The authors contribute equally to this work.
Academic Editor: Nuno Neng
Molecules 2019, 24(7), 1312; https://doi.org/10.3390/molecules24071312
Received: 24 February 2019 / Revised: 25 March 2019 / Accepted: 29 March 2019 / Published: 3 April 2019
(This article belongs to the Special Issue Modern Sample Preparation Approaches for Separation Science)
  |  
PDF [3662 KB, uploaded 3 April 2019]
  |     |  

Abstract

In this study, a green ionic-liquid based vortex-synchronized matrix solid-phase dispersion (VS-MSPD) combined with high performance liquid chromatography (HPLC) method was developed as a quantitative determination method for four anthraquinones in Cassiae Semen. Two conventional adsorbents, C18 and silica gel were investigated. The strategy included two steps: Extraction and determination. Wasted crab shells were used as an alternative adsorbent and ionic liquid was used as an alternative solvent in the first step. Factors affecting extraction efficiency were optimized: A sample/adsorbent ratio of 2:1, a grinding time of 3 min, a vortex time of 3 min, and ionic liquid ([Domim]HSO4, 250 mM) was used as eluent in the VS-MSPD procedure. As a result, the established method provided satisfactory linearity (R > 0.999), good accuracy and high reproducibility (RSD < 4.60%), and it exhibited the advantages of smaller sample amounts, shorter extraction time, less volume of elution solvent, and was much more environmental-friendly when compared with other conventional methods. View Full-Text
Keywords: vortex-synchronized matrix solid-phase dispersion; crab shells; ionic liquids; anthraquinones; Cassiae Semen vortex-synchronized matrix solid-phase dispersion; crab shells; ionic liquids; anthraquinones; Cassiae Semen
Figures

Graphical abstract

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
SciFeed

Share & Cite This Article

MDPI and ACS Style

Jiang, L.; Wang, J.; Zhang, H.; Liu, C.; Tang, Y.; Chu, C. New Vortex-Synchronized Matrix Solid-Phase Dispersion Method for Simultaneous Determination of Four Anthraquinones in Cassiae Semen. Molecules 2019, 24, 1312.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top