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Antioxidative Categorization of Twenty Amino Acids Based on Experimental Evaluation

College of Medical Laboratory, Dalian Medical University, Dalian 116044, China
Author to whom correspondence should be addressed.
Molecules 2017, 22(12), 2066;
Received: 19 October 2017 / Revised: 16 November 2017 / Accepted: 23 November 2017 / Published: 27 November 2017
PDF [749 KB, uploaded 27 November 2017]


In view of the great importance bestowed on amino acids as antioxidants in oxidation resistance, we attempted two common redox titration methods in this report, including micro-potassium permanganate titration and iodometric titration, to measure the antioxidative capacity of 20 amino acids, which are the construction units of proteins in living organisms. Based on the relative intensities of the antioxidative capacity, we further conducted a quantitative comparison and found out that the product of experimental values obtained from the two methods was proven to be a better indicator for evaluating the relative antioxidative capacity of amino acids. The experimental results were largely in accordance with structural analysis made on amino acids. On the whole, the 20 amino acids concerned could be divided into two categories according to their antioxidative capacity. Seven amino acids, including tryptophan, methionine, histidine, lysine, cysteine, arginine and tyrosine, were greater in total antioxidative capacity compared with the other 13 amino acids. View Full-Text
Keywords: amino acid; total antioxidant capability; redox titration amino acid; total antioxidant capability; redox titration

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Xu, N.; Chen, G.; Liu, H. Antioxidative Categorization of Twenty Amino Acids Based on Experimental Evaluation. Molecules 2017, 22, 2066.

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