Next Article in Journal
Achillolide A Protects Astrocytes against Oxidative Stress by Reducing Intracellular Reactive Oxygen Species and Interfering with Cell Signaling
Next Article in Special Issue
Genetic and Epigenetic Approaches for the Possible Detection of Adulteration and Auto-Adulteration in Saffron (Crocus sativus L.) Spice
Previous Article in Journal
Elucidation of Transport Mechanism of Paeoniflorin and the Influence of Ligustilide, Senkyunolide I and Senkyunolide A on Paeoniflorin Transport through Mdck-Mdr1 Cells as Blood–Brain Barrier in Vitro Model
Previous Article in Special Issue
On the Traceability of Commercial Saffron Samples Using 1H-NMR and FT-IR Metabolomics
Due to scheduled maintenance work on our core network, there may be short service disruptions on this website between 16:00 and 16:30 CEST on September 25th.
Review

Constituents of Saffron (Crocus sativus L.) as Potential Candidates for the Treatment of Anxiety Disorders and Schizophrenia

Department of Pharmacology, School of Medicine, Faculty of Health Sciences, University of Thessaly, Panepistimiou 3 (Biopolis), Larissa 41500, Greece
Academic Editors: Maria Z. Tsimidou and Petros A. Tarantilis
Molecules 2016, 21(3), 303; https://doi.org/10.3390/molecules21030303
Received: 8 December 2015 / Revised: 10 February 2016 / Accepted: 29 February 2016 / Published: 2 March 2016
Anxiety disorders and schizophrenia are common public health issues. The dried stigma of the plant Crocus sativus L., (C. sativus) commonly known as saffron are used in folk medicine for various purposes. Several lines of evidence suggest that C. sativus, crocins and safranal are implicated in anxiety and schizophrenia. Here, I intend to critically review advances in research of these emerging molecules for the treatment of anxiety and schizophrenia, discuss their advantages over currently used anxiolytics and neuroleptics, as well remaining challenges. Current analysis shows that C. sativus and its components might be a promising class of compounds for the treatment of the above mentioned psychiatric diseases. View Full-Text
Keywords: Crocus sativus L.; anxiety; stress; schizophrenia Crocus sativus L.; anxiety; stress; schizophrenia
Show Figures

Figure 1

MDPI and ACS Style

Pitsikas, N. Constituents of Saffron (Crocus sativus L.) as Potential Candidates for the Treatment of Anxiety Disorders and Schizophrenia. Molecules 2016, 21, 303. https://doi.org/10.3390/molecules21030303

AMA Style

Pitsikas N. Constituents of Saffron (Crocus sativus L.) as Potential Candidates for the Treatment of Anxiety Disorders and Schizophrenia. Molecules. 2016; 21(3):303. https://doi.org/10.3390/molecules21030303

Chicago/Turabian Style

Pitsikas, Nikolaos. 2016. "Constituents of Saffron (Crocus sativus L.) as Potential Candidates for the Treatment of Anxiety Disorders and Schizophrenia" Molecules 21, no. 3: 303. https://doi.org/10.3390/molecules21030303

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop