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Article

Secondary Metabolites from Sida rhombifolia L. (Malvaceae) and the Vasorelaxant Activity of Cryptolepinone

Postgraduate Program in Bioactive Natural and Synthetic Products, Health Sciences Center, Federal University of Paraíba, 58051-970, João Pessoa, PB, Brazil
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Molecules 2013, 18(3), 2769-2777; https://doi.org/10.3390/molecules18032769
Received: 7 December 2012 / Revised: 31 January 2013 / Accepted: 7 February 2013 / Published: 1 March 2013
The phytochemical study of Sida rhombifolia L. (Malvaceae) led to the isolation through chromatographic techniques of eleven secondary metabolites: sitosterol (1a) and stigmasterol (1b), sitosterol-3-O-b-D-glucopyranoside (2a) and stigmasterol-3-O-b-D-glucopyranoside (2b), phaeophytin A (3), 173-ethoxypheophorbide A (4), 132-hydroxy phaeophytin B (5), 173-ethoxypheophorbide B (6), 5,7-dihydroxy-4'-methoxyflavone (7), cryptolepinone (8) and a salt of cryptolepine (9). Their structures were identified by 1H- and 13C-NMR using one- and two-dimensional techniques. In addition, the vasorelaxant activity of cryptolepinone in rat mesenteric artery rings is reported herein for the first time. View Full-Text
Keywords: phytochemical study; Sida rhombifolia L.; Malvaceae; cryptolepinone; vasorelaxant activity phytochemical study; Sida rhombifolia L.; Malvaceae; cryptolepinone; vasorelaxant activity
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MDPI and ACS Style

Chaves, O.S.; Gomes, R.A.; Tomaz, A.C.d.A.; Fernandes, M.G.; Das Graças Mendes Junior, L.; De Fátima Agra, M.; Braga, V.A.; De Fátima Vanderlei de Souza, M. Secondary Metabolites from Sida rhombifolia L. (Malvaceae) and the Vasorelaxant Activity of Cryptolepinone. Molecules 2013, 18, 2769-2777. https://doi.org/10.3390/molecules18032769

AMA Style

Chaves OS, Gomes RA, Tomaz ACdA, Fernandes MG, Das Graças Mendes Junior L, De Fátima Agra M, Braga VA, De Fátima Vanderlei de Souza M. Secondary Metabolites from Sida rhombifolia L. (Malvaceae) and the Vasorelaxant Activity of Cryptolepinone. Molecules. 2013; 18(3):2769-2777. https://doi.org/10.3390/molecules18032769

Chicago/Turabian Style

Chaves, Otemberg S., Roosevelt A. Gomes, Anna C.d.A. Tomaz, Marianne G. Fernandes, Leônidas Das Graças Mendes Junior, Maria De Fátima Agra, Valdir A. Braga, and Maria De Fátima Vanderlei de Souza. 2013. "Secondary Metabolites from Sida rhombifolia L. (Malvaceae) and the Vasorelaxant Activity of Cryptolepinone" Molecules 18, no. 3: 2769-2777. https://doi.org/10.3390/molecules18032769

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