Ameliorative Effects of Curculigoside from Curculigo orchioides Gaertn on Learning and Memory in Aged Rats
Abstract
:1. Introduction
2. Results and Discussion
2.1. Effects of Curculigoside on Learning Performances in Aged Rats in the Step-Down Test
2.2. Effects of Curculigoside on Learning Performances in Aged Rats in the Y-Maze Test
2.3. Effects of Curculigoside on Cerebral Acetylcholinesterase Activity
2.4. Effect of Curculigoside on Expressions of BACE1
2.5. Discussion
3. Experimental
3.1. Plant Material
3.2. Animals
3.3. Sample Preparation
3.4. Drugs and Chemicals
3.5. Analysis of Curculigoside
3.6. Protocols
3.7. Preparation of AD Model Rats and Grouping
3.8. Step-Down Test
3.9. Y-maze Test
3.10. Measurement of AchE Activity
3.11. Western Blotting for Determination of BACE1Expression
3.12. Statistical Analysis
4. Conclusions
Conflicts of interest
References
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Wu, X.-Y.; Li, J.-Z.; Guo, J.-Z.; Hou, B.-Y. Ameliorative Effects of Curculigoside from Curculigo orchioides Gaertn on Learning and Memory in Aged Rats. Molecules 2012, 17, 10108-10118. https://doi.org/10.3390/molecules170910108
Wu X-Y, Li J-Z, Guo J-Z, Hou B-Y. Ameliorative Effects of Curculigoside from Curculigo orchioides Gaertn on Learning and Memory in Aged Rats. Molecules. 2012; 17(9):10108-10118. https://doi.org/10.3390/molecules170910108
Chicago/Turabian StyleWu, Xiu-Ying, Jian-Zhong Li, Jian-Zheng Guo, and Bao-Yuan Hou. 2012. "Ameliorative Effects of Curculigoside from Curculigo orchioides Gaertn on Learning and Memory in Aged Rats" Molecules 17, no. 9: 10108-10118. https://doi.org/10.3390/molecules170910108
APA StyleWu, X.-Y., Li, J.-Z., Guo, J.-Z., & Hou, B.-Y. (2012). Ameliorative Effects of Curculigoside from Curculigo orchioides Gaertn on Learning and Memory in Aged Rats. Molecules, 17(9), 10108-10118. https://doi.org/10.3390/molecules170910108