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Open AccessArticle

Synthesis and Sensory Evaluation of ent-Kaurane Diterpene Glycosides

1
Organic Chemistry Department, Global Research and Development, The Coca-Cola Company, One Coca-Cola Plaza, Atlanta, GA 30313, USA
2
Product Development, Coca-Cola North America Division, The Coca-Cola Company, One Coca-Cola Plaza, Atlanta, GA 30313, USA
3
Biosciences and Ingredient Department, Global Research and Development, The Coca-Cola Company, One Coca-Cola Plaza, Atlanta, GA 30313, USA
*
Author to whom correspondence should be addressed.
Molecules 2012, 17(8), 8908-8916; https://doi.org/10.3390/molecules17088908
Received: 29 June 2012 / Revised: 18 July 2012 / Accepted: 23 July 2012 / Published: 26 July 2012
(This article belongs to the Special Issue Advances in Carbohydrate Chemistry 2012)
Catalytic hydrogenation of the three ent-kaurane diterpene glycosides isolated from Stevia rebaudiana, namely rubusoside, stevioside, and rebaudioside-A has been carried out using Pd(OH)2 and their corresponding dihydro derivatives have been isolated as the products. Synthesis of reduced steviol glycosides was performed using straightforward chemistry and their structures were characterized on the basis of 1D and 2D NMR spectral data and chemical studies. Also, we report herewith the sensory evaluation of all the reduced compounds against their corresponding original steviol glycosides and sucrose for the sweetness property of these molecules. View Full-Text
Keywords: ent-kaurane diterpene glycosides; catalytic hydrogenation; Pd(OH)2; structure characterization; spectral data; chemical studies; sensory evaluation ent-kaurane diterpene glycosides; catalytic hydrogenation; Pd(OH)2; structure characterization; spectral data; chemical studies; sensory evaluation
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MDPI and ACS Style

Prakash, I.; Campbell, M.; San Miguel, R.I.; Chaturvedula, V.S.P. Synthesis and Sensory Evaluation of ent-Kaurane Diterpene Glycosides. Molecules 2012, 17, 8908-8916. https://doi.org/10.3390/molecules17088908

AMA Style

Prakash I, Campbell M, San Miguel RI, Chaturvedula VSP. Synthesis and Sensory Evaluation of ent-Kaurane Diterpene Glycosides. Molecules. 2012; 17(8):8908-8916. https://doi.org/10.3390/molecules17088908

Chicago/Turabian Style

Prakash, Indra; Campbell, Mary; San Miguel, Rafael Ignacio; Chaturvedula, Venkata Sai Prakash. 2012. "Synthesis and Sensory Evaluation of ent-Kaurane Diterpene Glycosides" Molecules 17, no. 8: 8908-8916. https://doi.org/10.3390/molecules17088908

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