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Open AccessArticle

Synthesis and Antimicrobial Activity of Some Pyridinium Salts

1
Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Ege University, 35100, Bornova, İzmir, Turkey
2
Department of Microbiology, Faculty of Pharmacy, Ege University, 35100 Bornova, İzmir, Turkey
*
Author to whom correspondence should be addressed.
Molecules 2009, 14(12), 5203-5215; https://doi.org/10.3390/molecules14125203
Received: 16 November 2009 / Revised: 4 December 2009 / Accepted: 10 December 2009 / Published: 14 December 2009
Some substituted benzylidenehydrazinylpyridinium derivatives bearing benzyl, ethylphenyl and propylphenyl groups on the pyridinium nitrogen were synthesized and screened for possible antibacterial and antifungal activities against Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa and Candida albicans using the microdilution method. Antimicrobial test results indicated that compounds containing a 3-phenylpropyl chain displayed the highest antimicrobial activity against Staphylococcus aureus and the compound 3d was the most active in the series against all tested bacteria and fungi strains. View Full-Text
Keywords: hydrazones; pyridinium salts; synthesis; antimicrobial activity hydrazones; pyridinium salts; synthesis; antimicrobial activity
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MDPI and ACS Style

Alptüzün, V.; Parlar, S.; Taşlı, H.; Erciyas, E. Synthesis and Antimicrobial Activity of Some Pyridinium Salts. Molecules 2009, 14, 5203-5215.

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