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Keywords = vision degrading myodesopsia

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20 pages, 1307 KB  
Review
Vitreous Antioxidants, Degeneration, and Vitreo-Retinopathy: Exploring the Links
by Emmanuel Ankamah, J. Sebag, Eugene Ng and John M. Nolan
Antioxidants 2020, 9(1), 7; https://doi.org/10.3390/antiox9010007 - 20 Dec 2019
Cited by 68 | Viewed by 17230
Abstract
The transparent vitreous body, which occupies about 80% of the eye’s volume, is laden with numerous enzymatic and non-enzymatic antioxidants that could protect the eye from oxidative stress and disease. Aging is associated with degeneration of vitreous structure as well as a reduction [...] Read more.
The transparent vitreous body, which occupies about 80% of the eye’s volume, is laden with numerous enzymatic and non-enzymatic antioxidants that could protect the eye from oxidative stress and disease. Aging is associated with degeneration of vitreous structure as well as a reduction in its antioxidant capacity. A growing body of evidence suggests these age-related changes may be the precursor of numerous oxidative stress-induced vitreo-retinopathies, including vision degrading myodesopsia, the clinically significant entoptic phenomena that can result from advanced vitreous degeneration. Adequate intravitreal antioxidant levels may be protective against vitreous degeneration, possibly preventing and even improving vision degrading myodesopsia as well as mitigating various other vitreo-retinopathies. The present article is, therefore, a review of the different antioxidant molecules within vitreous and the inter-relationships between vitreous antioxidant capacity and degeneration. Full article
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