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Keywords = triazolofullerenes

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4 pages, 383 KB  
Proceeding Paper
Fullerenyl-1,2,3-Triazoles: Synthesis and Cytotoxic Activity
by Zarema R. Sadretdinova, Arslan R. Akhmetov, Lilya U. Dzhemileva, Vladimir A. D’yakonov, Airat Tuktarov and Usein Dzhemilev
Chem. Proc. 2022, 8(1), 96; https://doi.org/10.3390/ecsoc-25-11659 - 13 Nov 2021
Cited by 1 | Viewed by 1018
Abstract
Through the reaction of fullerenylazide with terminal acetylenes, previously undescribed 1-butyl-2-triazolylfullerenes, in which the heterocyclic fragment was directly attached to the fullerene backbone, were synthesized for the first time. Water-soluble complexes of the synthesized adducts of fullerene with polyvinylpyrrolidone showed a high cytotoxic [...] Read more.
Through the reaction of fullerenylazide with terminal acetylenes, previously undescribed 1-butyl-2-triazolylfullerenes, in which the heterocyclic fragment was directly attached to the fullerene backbone, were synthesized for the first time. Water-soluble complexes of the synthesized adducts of fullerene with polyvinylpyrrolidone showed a high cytotoxic activity towards tumor cells of the Jurkat, K562, and U937 lines. Full article
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