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Keywords = signet ring cell mesothelioma

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8 pages, 8667 KiB  
Brief Report
Unusual Histology in Mesothelioma: A Report of Two Cases with a Brief Review
by Francesca Bono, Stefano Ceola, Carlo Beretta and Marta Jaconi
Diagnostics 2022, 12(2), 371; https://doi.org/10.3390/diagnostics12020371 - 1 Feb 2022
Cited by 3 | Viewed by 2768
Abstract
Mesothelioma is often difficult to diagnose due to its rarity and its unusual histopathological features that could lend to diagnostic pitfalls and misdiagnosis. The WHO histological classification of pleural tumors in 2021 recommended a pathologic grading system for malignant pleural mesothelioma. Architectural aspects [...] Read more.
Mesothelioma is often difficult to diagnose due to its rarity and its unusual histopathological features that could lend to diagnostic pitfalls and misdiagnosis. The WHO histological classification of pleural tumors in 2021 recommended a pathologic grading system for malignant pleural mesothelioma. Architectural aspects and cytological features, with nuclear grading, bent on a neoplastic score with fundamental prognostic and diagnostic value. Unusual features must be correctly assigned in the grading system to avoid misdiagnosis, especially toward metastatic lesions or reactive pleural processes. In this paper, we present two cases as examples of unusual morphological and architectural features with a brief literature review. Full article
(This article belongs to the Special Issue Recent Advances in Diagnosis of Malignant Mesothelioma)
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