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Keywords = rota-lithotripsy

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12 pages, 1521 KiB  
Article
Rota-Lithotripsy as a Novel Bail-Out Strategy for Highly Calcified Coronary Lesions in Acute Coronary Syndrome
by Piotr Rola, Łukasz Furtan, Szymon Włodarczak, Jan Jakub Kulczycki, Mateusz Barycki, Marek Szudrowicz, Michalina Kędzierska, Anna Pszonka, Justyna Korus, Adrian Doroszko, Maciej Lesiak and Adrian Włodarczak
Biomedicines 2022, 10(11), 2795; https://doi.org/10.3390/biomedicines10112795 - 3 Nov 2022
Cited by 4 | Viewed by 2351
Abstract
Background: Heavily calcified lesions in acute coronary syndrome (ACS) still represent a challenging subset for percutaneous coronary intervention (PCI). Rota-lithotripsy—a marriage of rotational atherectomy and intravascular lithotripsy—has recently been introduced to clinical practice as a novel therapeutic option. Methods: This study is among [...] Read more.
Background: Heavily calcified lesions in acute coronary syndrome (ACS) still represent a challenging subset for percutaneous coronary intervention (PCI). Rota-lithotripsy—a marriage of rotational atherectomy and intravascular lithotripsy—has recently been introduced to clinical practice as a novel therapeutic option. Methods: This study is among the to present the 6-month clinical outcomes of rota-lithotripsy when performed in the ACS setting. The study cohort consisted of 15 consecutive ACS patients who underwent a rota-lithotripsy-PCI due to the presence of a highly calcified, undilatable lesion. Results: The procedural success ratio reached 100%. During the 6-month follow-up, in two of the patients, instances of MACE (major adverse cardiac events) occurred, including one fatal event. Additionally, during the observation period, one target lesion failure, due to subacute stent thrombosis, was identified. Conclusions: Rotational atherectomy with the subsequent use of shockwave intravascular lithotripsy appears to be a safe and effective therapeutic bail-out option for the management of highly calcified coronary artery lesions. Despite, these initial favorable outcomes, carrying out a large number of studies with long-term observations is still necessary in order to establish the potential benefits and shortcomings of rota-lithotripsy. Full article
(This article belongs to the Special Issue Advances in Cardiovascular Diseases (CVD))
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12 pages, 1462 KiB  
Article
Intravascular Lithotripsy as a Novel Treatment Method for Calcified Unprotected Left Main Diseases—Comparison to Rotational Atherectomy—Short-Term Outcomes
by Piotr Rola, Jan Jakub Kulczycki, Adrian Włodarczak, Mateusz Barycki, Szymon Włodarczak, Marek Szudrowicz, Łukasz Furtan, Artur Jastrzębski, Maciej Pęcherzewski, Maciej Lesiak and Adrian Doroszko
Int. J. Environ. Res. Public Health 2022, 19(15), 9011; https://doi.org/10.3390/ijerph19159011 - 25 Jul 2022
Cited by 17 | Viewed by 3642
Abstract
Background: The unprotected calcified Left Main disease represents a high-risk subset for percutaneous coronary intervention (PCI), and it is associated with a higher number of periprocedural complications and an increased rate of in-stent thrombosis and restenosis. Adequate lesion preparation plays a crucial role [...] Read more.
Background: The unprotected calcified Left Main disease represents a high-risk subset for percutaneous coronary intervention (PCI), and it is associated with a higher number of periprocedural complications and an increased rate of in-stent thrombosis and restenosis. Adequate lesion preparation plays a crucial role in achieving a favorable PCI outcome. Rotational Atherectomy (RA) is a well-established plaque-modifying method; nevertheless, the data regarding the effectiveness of RA in LM diseases is scarce. Recently, the novel ShockWave-Intravascular-Lithotripsy(S-IVL) device has been introduced to the PCI armamentarium in order to modify the calcified plaque. Methods: We performed a retrospective evaluation of 44 consecutive subjects who underwent the LM-PCI, and who were supported by either the RA or S-IVL. Results: The Rota group consisted of 29 patients with a mean syntax score of 28.0 ± 7.5. The S-IVL group was composed of 15 subjects with a syntax score of 23.3 ± 13.0 There were no statistical differences regarding MACE between the RA and Shockwave arms of the in-hospital group (10.3% vs. 6.7%), or in the six month (17.2% vs. 13.3%) follow-up group. Conclusions: RA and S-IVL could be safe and effective therapeutic strategies for calcified LM disease. Further studies with a higher number of participants and longer follow-up times are warranted to establish the potential benefits of RA and S-IVL for the management of LM stenosis. Full article
(This article belongs to the Special Issue Vascular Disease and Health)
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10 pages, 1087 KiB  
Article
Rota-Lithotripsy—A Novel Bail-Out Strategy for Calcified Coronary Lesions in Acute Coronary Syndrome. The First-in-Man Experience
by Adrian Włodarczak, Piotr Rola, Mateusz Barycki, Jan Jakub Kulczycki, Marek Szudrowicz, Maciej Lesiak and Adrian Doroszko
J. Clin. Med. 2021, 10(9), 1872; https://doi.org/10.3390/jcm10091872 - 26 Apr 2021
Cited by 13 | Viewed by 2564
Abstract
Heavy calcification remains one of the greatest challenges in the treatment of coronary artery disease (CAD), especially in subjects with an acute coronary syndrome (ACS). In the present case series study of high-risk patients with ACS, including both STEMI and NSTEMI, we performed [...] Read more.
Heavy calcification remains one of the greatest challenges in the treatment of coronary artery disease (CAD), especially in subjects with an acute coronary syndrome (ACS). In the present case series study of high-risk patients with ACS, including both STEMI and NSTEMI, we performed a rota-lithotripsy—a combination of rotational atherectomy with subsequent intravascular lithotripsy—as a novel bail-out strategy to facilitate stent delivery in a tortuous calcified coronary artery. Full article
(This article belongs to the Special Issue New Frontiers in Cardiovascular Intervention)
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