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Keywords = pyridinimine

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16 pages, 3238 KiB  
Article
Primary Pyrrolimines and Pyridinimines
by Amavi Kpoezoun, Gnon Baba and Jean-Claude Guillemin
Molecules 2025, 30(6), 1239; https://doi.org/10.3390/molecules30061239 - 10 Mar 2025
Viewed by 781
Abstract
The association of an aromatic ring with an N-H-unsubstituted imine generates families of compounds that have been little studied until now except when the ring is a phenyl group. Recently, such imines substituted by a furan or thiophene group have been synthesized. This [...] Read more.
The association of an aromatic ring with an N-H-unsubstituted imine generates families of compounds that have been little studied until now except when the ring is a phenyl group. Recently, such imines substituted by a furan or thiophene group have been synthesized. This work reports a similar study where a pyrrole or pyridine ring is directly linked to an N-unsubstituted aldimine or ketimine group in order to isolate such compounds and to open the way to the knowledge of their physicochemical properties. The lower volatility of pyrrole and pyridine derivatives compared to aryl, furan, or thiophene derivatives greatly increases the difficulty of the synthesis and isolation of these kinetically unstable compounds. Full article
(This article belongs to the Section Organic Chemistry)
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