5 Results Found

Advanced Search

Select all

Results per page

Select all

Article

23 Citations

11,473 Views

18 Pages

Studies on the Mechanisms of Anti-Inflammatory Activity of Heparin- and Hyaluronan-Containing Multilayer Coatings—Targeting NF-κB Signalling Pathway

Hala Alkhoury,
Adrian Hautmann,
Bodo Fuhrmann,
Frank Syrowatka,
Frank Erdmann,
Guoying Zhou,
Sanja Stojanović,
Stevo Najman and
Thomas Groth

Int. J. Mol. Sci.2020, 21(10), 3724;https://doi.org/10.3390/ijms21103724

25 May 2020

The use of implants can be hampered by chronic inflammatory reactions, which may result in failure of the implanted device. To prevent such an outcome, the present study examines the anti-inflammatory properties of surface coatings made of either hya...

Full Article

Review

21 Citations

8,218 Views

10 Pages

Multinucleated Giant Cell Formation as a Portal to Chronic Bacterial Infections

Jacob L. Stockton and
Alfredo G. Torres

Microorganisms2020, 8(11), 1637;https://doi.org/10.3390/microorganisms8111637

23 October 2020

This review provides a snapshot of chronic bacterial infections through the lens of Burkholderia pseudomallei and detailing its ability to establish multi-nucleated giant cells (MNGC) within the host, potentially leading to the formation of pyogranul...

Full Article

Article

11 Citations

3,369 Views

24 Pages

In Vitro and In Vivo Cell-Interactions with Electrospun Poly (Lactic-Co-Glycolic Acid) (PLGA): Morphological and Immune Response Analysis

Ana Chor,
Christina Maeda Takiya,
Marcos Lopes Dias,
Raquel Pires Gonçalves,
Tatiana Petithory,
Jefferson Cypriano,
Leonardo Rodrigues de Andrade,
Marcos Farina and
Karine Anselme

Polymers2022, 14(20), 4460;https://doi.org/10.3390/polym14204460

21 October 2022

Random electrospun three-dimensional fiber membranes mimic the extracellular matrix and the interfibrillar spaces promotes the flow of nutrients for cells. Electrospun PLGA membranes were analyzed in vitro and in vivo after being sterilized with gamm...

Full Article

Article

6 Citations

3,739 Views

13 Pages

Endochondral Ossification Induced by Cell Transplantation of Endothelial Cells and Bone Marrow Stromal Cells with Copolymer Scaffold Using a Rat Calvarial Defect Model

Zhe Xing,
Xiaofeng Jiang,
Qingzong Si,
Anna Finne-Wistrand,
Bin Liu,
Ying Xue and
Kamal Mustafa

Polymers2021, 13(9), 1521;https://doi.org/10.3390/polym13091521

9 May 2021

It has been recently reported that, in a rat calvarial defect model, adding endothelial cells (ECs) to a culture of bone marrow stromal cells (BMSCs) significantly enhanced bone formation. The aim of this study is to further investigate the ossificat...

Full Article

Article

3 Citations

3,061 Views

13 Pages

Anti-Hcp1 Monoclonal Antibody Is Protective against Burkholderia pseudomallei Infection via Recognizing Amino Acids at Asp95-Leu114

Pan Wu,
Chenglong Rao,
Wenzheng Liu,
Ziyuan Zhang,
Dongqi Nan,
Jiangao Chen,
Minyang Wang,
Yuan Wen,
Jingmin Yan and
Qian Li
+ 2 authors

Pathogens2024, 13(1), 43;https://doi.org/10.3390/pathogens13010043

31 December 2023

Melioidosis, a severe tropical illness caused by Burkholderia pseudomallei, poses significant treatment challenges due to limited therapeutic options and the absence of effective vaccines. The pathogen’s intrinsic resistance to numerous antibio...

Full Article