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This study analyzes the marginal bone loss (MBL) among dental implants characterized with non-threaded collar design (NT) when compared to the more classic micro-threaded collar design (MC) as such might reflect the future dentogengival esthetics, implant metal show, and mucositis. A total of 112 patients who received 311 implants have been included in the study and analyzed for their postoperative MBL using sequential periapical radiographs. The prevalence of postoperative peri-implant mucositis was recorded as well. The periapical radiographic comparison was performed between the immediate postoperative record and at the 24-month recall visit. Among the 311 implants, 124 (39.9%) had NT implants, and 187 (60.1%) had MC implants. Out of the 112 patients, 37 (44.6%) were females, and 10 (34.5%) were males included in the NT group. In contrast, 46 (55.4%) females and 19 (65.5%) males were in the MC group. The mean age among the two groups was 41.43 ± 15.900 and 46.68 ± 16.070, respectively. In contrast, the mean MBL among the groups were 0.544 ± 0.7129 and 0.061 ± 0.2648, respectively. The change in MBL was not positively correlated with gender (p-value = 0.154) or age (p-value = 0.115) in both groups. However, there was a significant difference (p-value = 0.001, X² = 62.796, Df = 4) of MBL between the two implant systems themselves. The MBL was higher in people implanted with the NT system when compared to MC. Therefore, the MC implant system can be a better choice for marginal bone preservation, especially in restoring esthetically demanding areas in the mouth. Full article