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Article

713 Views

13 Pages

Advances in Isofuranodiene Extraction from Smyrnium olusatrum L.: Supercritical Carbon Dioxide Extraction

Eleonora Spinozzi,
Giada Trebaiocchi,
Riccardo Petrelli,
Francesco Di Monaco and ,
Marco Cespi and
Filippo Maggi
+ 1 author+ 0 author

Plants2026, 15(7), 1099;https://doi.org/10.3390/plants15071099

3 April 2026

Supercritical CO₂ (S-CO₂) extraction is one of the most employed techniques for the extraction of bioactive compounds for its safety, effectiveness, cost-efficiency, and good environmental compliance. Smyrnium olusatrum L. (Apiaceae) is an aromatic p...

(This article belongs to the Section Phytochemistry)

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Article

18 Citations

4,390 Views

9 Pages

In Vitro Scolicidal Activity of the Sesquiterpenes Isofuranodiene, α-Bisabolol and Farnesol on Echinococcus granulosus Protoscoleces

Mohammad Reza Youssefi,
Ali Nikpay,
Niloufar Hassanpour,
Aida Mirzapour and ,
Parisa Saleh Tabari,
Roman Pavela,
Filippo Maggi and
Riccardo Petrelli
+ 3 authors+ 0 author

Molecules2020, 25(16), 3593;https://doi.org/10.3390/molecules25163593

7 August 2020

Cystic echinococcosis (CE) remains an important challenge both in humans and animals. There is no safe and suitable remedy for CE, so the discovery of new compounds with promising scolicidal effects, particularly from herbal sources, is of great impo...

(This article belongs to the Collection Bioactive Compounds)

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18 Citations

3,548 Views

9 Pages

Isofuranodiene, a Natural Sesquiterpene Isolated from Wild Celery (Smyrnium olusatrum L.), Protects Rats against Acute Ischemic Stroke

Hasan Yousefi-Manesh,
Ahmad Reza Dehpour,
Samira Shirooie,
Fariba Bagheri and ,
Vida Farrokhi,
Seyyedeh Elaheh Mousavi,
Massimo Ricciutelli,
Loredana Cappellacci,
Víctor López and
Riccardo Petrelli
+ 6 authors+ 1 author

Pharmaceuticals2021, 14(4), 344;https://doi.org/10.3390/ph14040344

9 April 2021

The myrrh-like furanosesquiterpene isofuranodiene (IFD) is the main constituent of wild celery (Smyrnium olusatrum L., Apiaceae), an overlooked vegetable that was cultivated during the Roman Empire. In the present study, we investigated the protectiv...

(This article belongs to the Special Issue Plant and Marine-Derived Natural Product Research in Drug Discovery: Strengths and Perspective)

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