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Keywords = flexibilisquinone

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8 pages, 514 KiB  
Article
Flexibilisquinone, a New Anti-Inflammatory Quinone from the Cultured Soft Coral Sinularia flexibilis
by Yu-Fang Lin, Chao-Ying Kuo, Zhi-Hong Wen, Yen-You Lin, Wei-Hsien Wang, Jui-Hsin Su, Jyh-Horng Sheu and Ping-Jyun Sung
Molecules 2013, 18(7), 8160-8167; https://doi.org/10.3390/molecules18078160 - 10 Jul 2013
Cited by 30 | Viewed by 5792
Abstract
A new quinone derivative, flexibilisquinone (1), was isolated from the cultured soft coral Sinularia flexibilis, originally distributed in the waters of Taiwan. The structure of quinone 1 was established by extensive spectroscopic methods, particularly 1D and 2D NMR experiments. In [...] Read more.
A new quinone derivative, flexibilisquinone (1), was isolated from the cultured soft coral Sinularia flexibilis, originally distributed in the waters of Taiwan. The structure of quinone 1 was established by extensive spectroscopic methods, particularly 1D and 2D NMR experiments. In the in vitro anti-inflammatory effects test, quinone 1 was found to significantly inhibit the accumulation of the pro-inflammatory iNOS and COX-2 proteins of the LPS-stimulated RAW264.7 macrophage cells. Full article
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