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Keywords = dynamic conformal arc therapy (DCAT)

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13 pages, 710 KiB  
Review
Stereotactic Radiosurgery of Multiple Brain Metastases: A Review of Treatment Techniques
by Raphael Bodensohn, Sebastian H. Maier, Claus Belka, Giuseppe Minniti and Maximilian Niyazi
Cancers 2023, 15(22), 5404; https://doi.org/10.3390/cancers15225404 - 14 Nov 2023
Cited by 8 | Viewed by 3233
Abstract
The advancement of systemic targeted treatments has led to improvements in the management of metastatic disease, particularly in terms of survival outcomes. However, brain metastases remain less responsive to systemic therapies, underscoring the significance of local interventions for comprehensive disease control. Over the [...] Read more.
The advancement of systemic targeted treatments has led to improvements in the management of metastatic disease, particularly in terms of survival outcomes. However, brain metastases remain less responsive to systemic therapies, underscoring the significance of local interventions for comprehensive disease control. Over the past years, the threshold for treating brain metastases through stereotactic radiosurgery has risen. Yet, as the number of treated metastases increases, treatment complexity and duration also escalate. This trend has made multi-isocenter radiosurgery treatments, such as those with the Gamma Knife, challenging to plan and lengthy for patients. In contrast, single-isocenter approaches employing linear accelerators offer an efficient and expeditious treatment option. This review delves into the literature, comparing different linear-accelerator-based techniques with each other and in relation to dedicated systems, focusing on dosimetric considerations and feasibility. Full article
(This article belongs to the Special Issue Advances in Modern Radiation Oncology)
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