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Keywords = copper contact killing/inactivation

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14 pages, 1596 KiB  
Article
Effectiveness and Applications of a Metal-Coated HNT/Polylactic Acid Antimicrobial Filtration System
by Antwine W. McFarland, Anusha Elumalai, Christopher C. Miller, Ahmed Humayun and David K. Mills
Polymers 2022, 14(8), 1603; https://doi.org/10.3390/polym14081603 - 14 Apr 2022
Cited by 14 | Viewed by 3189
Abstract
A broad-spectrum antimicrobial respiration apparatus designed to fight bacteria, viruses, fungi, and other biological agents is critical in halting the current pandemic’s trajectory and containing future outbreaks. We applied a simple and effective electrodeposition method for metal (copper, silver, and zinc) coating the [...] Read more.
A broad-spectrum antimicrobial respiration apparatus designed to fight bacteria, viruses, fungi, and other biological agents is critical in halting the current pandemic’s trajectory and containing future outbreaks. We applied a simple and effective electrodeposition method for metal (copper, silver, and zinc) coating the surface of halloysite nanotubes (HNTs). These nanoparticles are known to possess potent antiviral and antimicrobial properties. Metal-coated HNTs (mHNTs) were then added to polylactic acid (PLA) and extruded to form an mHNT/PLA 3D composite printer filament. Our composite 3D printer filament was then used to fabricate an N95-style mask with an interchangeable/replaceable filter with surfaces designed to inactivate a virus and kill bacteria on contact, thus reducing deadly infections. The filter, made of a multilayered antimicrobial/mHNT blow spun polymer and fabric, is disposable, while the mask can be sanitized and reused. We used several in vitro means of assessing critical clinical features and assessed the bacterial growth inhibition against commonly encountered bacterial strains. These tests demonstrated the capability of our antimicrobial filament to fabricate N95 masks and filters that possessed antibacterial capabilities against both Gram-negative and Gram-positive bacteria. Full article
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43 pages, 17502 KiB  
Article
Understanding the Antipathogenic Performance of Nanostructured and Conventional Copper Cold Spray Material Consolidations and Coated Surfaces
by Bryer C. Sousa, Kristin L. Sundberg, Matthew A. Gleason and Danielle L. Cote
Crystals 2020, 10(6), 504; https://doi.org/10.3390/cryst10060504 - 12 Jun 2020
Cited by 17 | Viewed by 5847
Abstract
The role of high strain rate and severe plastic deformation, microstructure, electrochemical behavior, surface chemistry and surface roughness were characterized for two copper cold spray material consolidations, which were produced from conventionally gas-atomized copper powder as well as spray-dried copper feedstock, during the [...] Read more.
The role of high strain rate and severe plastic deformation, microstructure, electrochemical behavior, surface chemistry and surface roughness were characterized for two copper cold spray material consolidations, which were produced from conventionally gas-atomized copper powder as well as spray-dried copper feedstock, during the course of this work. The motivation underpinning this work centers upon the development of a more robust understanding of the microstructural features and properties of the conventional copper and nanostructured copper coatings as they relate to antipathogenic contact killing and inactivation applications. Prior work has demonstrated greater antipathogenic efficacy with respect to the nanostructured coating versus the conventional coating. Thus, microstructural analysis was performed in order to establish differences between the two coatings that their respective pathogen kill rates could be attributed to. Results from advanced laser-induced projectile impact testing, X-ray diffraction, scanning electron microscopy, electron backscatter diffraction, scanning transmission microscopy, nanoindentation, energy-dispersive X-ray spectroscopy, nanoindentation, confocal microscopy, atomic force microscopy, linear polarization, X-ray photoelectron spectroscopy, electrochemical impedance spectroscopy and copper ion release assaying were performed during the course of this research. Full article
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