Search Results (3)

A continuous flow with reagent injection method on a novel inlaid microfluidic platform for nitrite determination has been successfully developed. The significance of the high-frequency monitoring of nutrient fluctuations in marine environments is crucial for understanding our impacts on the ecosystem. Many in-situ systems face limitations in high-frequency data collection and have restricted deployment times due to high reagent consumption. The proposed microfluidic device employs automatic colorimetric absorbance spectrophotometry, using the Griess assay for nitrite determination, with minimal reagent usage. The sensor incorporates 10 solenoid valves, four syringes, two LEDs, four photodiodes, and an inlaid microfluidic technique to facilitate optical measurements of fluid volumes. In this flow system, Taylor–Aris dispersion was simulated for different injection volumes at a constant flow rate, and the results have been experimentally confirmed using red food dye injection into a carrier stream. A series of tests were conducted to determine a suitable injection frequency for the reagent. Following the initial system characterization, seven different standard concentrations ranging from 0.125 to 10 µM nitrite were run through the microfluidic device to acquire a calibration curve. Three different calibrations were performed to optimize plug length, with reagent injection volumes of 4, 20, and 50 µL. A straightforward signal processing method was implemented to mitigate the Schlieren effect caused by differences in refractive indexes between the reagent and standards. The results demonstrate that a sampling frequency of at least 10 samples per hour is achievable using this system. The obtained attenuation coefficients exhibited good agreement with the literature, while the reagent consumption was significantly reduced. The limit of detection for a 20 µL injection volume was determined to be 94 nM from the sample intake, and the limit of quantification was 312 nM. Going forward, the demonstrated system will be packaged in a submersible enclosure to facilitate in-situ colorimetric measurements in marine environments. Full article

Fluid intake monitoring is an essential component in preventing dehydration and overhydration, especially for the senior population. Numerous critical health problems are associated with poor or excessive drinking such as swelling of the brain and heart failure. Real-time systems for monitoring fluid intake will not only measure the exact amount consumed by the users, but could also motivate people to maintain a healthy lifestyle by providing feedback to encourage them to hydrate regularly throughout the day. This paper reviews the most recent solutions to automatic fluid intake monitoring both commercially and in the literature. The available technologies are divided into four categories: wearables, surfaces with embedded sensors, vision- and environmental-based solutions, and smart containers. A detailed performance evaluation was carried out considering detection accuracy, usability and availability. It was observed that the most promising results came from studies that used data fusion from multiple technologies, compared to using an individual technology. The areas that need further research and the challenges for each category are discussed in detail. Full article

Various sensors have been proposed to address the negative health ramifications of inadequate fluid consumption. Amongst these solutions, motion-based sensors estimate fluid intake using the characteristics of drinking kinematics. This sensing approach is complicated due to the mutual influence of both the drink volume and the current fill level on the resulting motion pattern, along with differences in biomechanics across individuals. While motion-based strategies are a promising approach due to the proliferation of inertial sensors, previous studies have been characterized by limited accuracy and substantial variability in performance across subjects. This research seeks to address these limitations for a container-attachable triaxial accelerometer sensor. Drink volume is computed using support vector machine regression models with hand-engineered features describing the container’s estimated inclination. Results are presented for a large-scale data collection consisting of 1908 drinks consumed from a refillable bottle by 84 individuals. Per-drink mean absolute percentage error is reduced by 11.05% versus previous state-of-the-art results for a single wrist-wearable inertial measurement unit (IMU) sensor assessed using a similar experimental protocol. Estimates of aggregate consumption are also improved versus previously reported results for an attachable sensor architecture. An alternative tracking approach using the fill level from which a drink is consumed is also explored herein. Fill level regression models are shown to exhibit improved accuracy and reduced inter-subject variability versus volume estimators. A technique for segmenting the entire drink motion sequence into transport and sip phases is also assessed, along with a multi-target framework for addressing the known interdependence of volume and fill level on the resulting drink motion signature. Full article