Search Results (6)

This paper delineates the theology of creation in Brazilian theologian Cláudio Carvalhaes’ eco-liturgical theology of liberation. Reorienting lex orandi-lex credendi-lex vivendi by his liturgical methodological innovation lex naturae, he envisions every dimension of worship as deeply connected to a planet in crisis. Lex naturae transforms liturgical spaces into creational–political spaces which invoke and evoke people to deeply attend to, to cry with, to wonder with, and to pray and sing with the forests, animals, soil, water, and all earthly beings. Celebrating a creational solidarity and wisdom, lex naturae ritualizes that people are the earth, the earth is in people, and human and more-than-human beings belong to each other. Using the seven petitions of his “The Ecological Lord’s Prayer”, Carvalhaes’ theology of creation, which reimagines the Divine, the earth, and the human in a multispecies context via the (re)orienting ground of lex naturae, is “unearthed.” His theology of creation centers the creaturely commonality with more-than-human neighbors and challenges human beings to live, love, and flourish within all the entanglements of created life. Lex naturae is also a form of asceticism which aims to recalibrate the human focus towards environmental justice for the planet. It aims at changing human desire to turn away from the brutalism of colonialism’s ecocide and toward wholesome relations with animals, plants, soil, land, and water. In the end, this paper claims that Carvalhaes’ theology of creation affirms a “godly animism”. Full article

Cell-based therapies using corneal stromal stem cells (CSSC), corneal keratocytes, or a combination of both suppress corneal scarring. The number of quiescent keratocytes in the cornea is small; it is difficult to expand them in vitro in quantities suitable for transplantation. This study examined the therapeutic effect of corneal fibroblasts reversed into keratocytes (rCF) in a mouse model of mechanical corneal injury. The therapeutic effect of rCF was studied in vivo (slit lamp, optical coherence tomography) and ex vivo (transmission electron microscopy and immunofluorescence staining). Injection of rCF into the injured cornea was accompanied by recovery of corneal thickness, improvement of corneal transparency, reduction of type III collagen in the stroma, absence of myofibroblasts, and the improvement in the structural organization of collagen fibers. TEM results showed that 2 months after intrastromal injection of cells, there was a decrease in the fibril density and an increase in the fibril diameter and the average distance between collagen fibrils. The fibrils were well ordered and maintained the short-range order and the number of nearest-neighbor fibrils, although the averaged distance between them increased. Our results demonstrated that the cell therapy of rCF from ReLEx SMILe lenticules promotes the recovery of transparent corneal stroma after injury. Full article

Background: In this study, the changes in corneal cap and residual stromal thickness (RST) values during a 180-day observation period after refractive lenticule extraction small incision lenticule extraction (ReLEx SMILE) were assessed. Methods: Fifty patients underwent ReLEx SMILE using the VisuMax 500 femtosecond laser, with corneal imaging conducted pre and post procedure via anterior segment optical coherence tomography (AS-OCT). Cap thickness in the center and 1.5 mm from the center in four meridians was measured at various intervals. Results: The results showed a significant decrease in cap thickness 180 days post procedure compared to earlier intervals (p < 0.05). Similarly, RST decreased gradually and significantly post procedure (p < 0.05). Notably, changes in cap thickness within the central 1.5 mm area were more dynamic than RST changes during the 6-month observation period following SMILE. Conclusions: The corneal cap thickness measured with swept-source AS-OCT within the central 1.5 mm area underwent more dynamic changes than the residual stromal thickness during the 6-month observation following SMILE. Full article

Arranging products in stores according to planograms, optimized product arrangement maps, is an important sales enabler and necessary for keeping up with the highly competitive modern retail market. Key benefits of planograms include increased efficiency, maximized retail store space, increased customer satisfaction, visual appeal, and increased revenue. The planograms are realized into product arrangements by humans, a process that is prone to mistakes. Therefore, for optimal merchandising performance, the planogram compliance of the arrangements needs to be evaluated from time to time. We investigate utilizing a computer vision problem setting—retail product detection—to automate planogram compliance evaluation. Retail product detection comprises product detection and classification. The detected and classified products can be compared to the planogram in order to evaluate compliance. In this paper, we propose a novel retail product detection pipeline combining a Gaussian layer network product proposal generator and domain invariant hierarchical embedding (DIHE) classifier. We utilize the detection pipeline with RANSAC pose estimation for planogram compliance evaluation. As the existing metrics for evaluating the planogram compliance evaluation performance assume unrealistically that the test image matches the planogram, we propose a novel metric, called normalized planogram compliance error $\left(E_{PC}\right)$, for benchmarking real-world setups. We evaluate the performance of our method with two datasets: the only open-source dataset with planogram evaluation data, GP-180, and our own dataset collected from a large Nordic retailer. Based on the evaluation, our method provides an improved planogram compliance evaluation pipeline, with accurate product location estimation when using real-life images that include entire shelves, unlike previous research that has only used images with few products. Our analysis also demonstrates that our method requires less processing time than the state-of-the-art compliance evaluation methods. Full article

Fibroblasts isolated and expanded from ReLEx SMILE lenticules can be a source of human keratocytes. Since corneal keratocytes are quiescent cells, it is difficult to expand them in vitro in suitable numbers for clinical and experimental use. In the present study, this problem was solved by isolating and growing corneal fibroblasts (CFs) with a high proliferative potential and their reversion to keratocytes in a selective serum-free medium. Fibroblasts reversed into keratocytes (rCFs) had a dendritic morphology and ultrastructural signs of activation of protein synthesis and metabolism. The cultivation of CFs in a medium with 10% FCS and their reversion into keratocytes was not accompanied by the induction of myofibroblasts. After reversion, the cells spontaneously formed spheroids and expressed keratocan and lumican markers, but not mesenchymal ones. The rCFs had low proliferative and migratory activity, and their conditioned medium contained a low level of VEGF. CF reversion was not accompanied by a change with the levels of IGF-1, TNF-alpha, SDF-1a, and sICAM-1. In the present study, it has been demonstrated that fibroblasts from ReLEx SMILE lenticules reverse into keratocytes in serum-free KGM, maintaining the morphology and functional properties of primary keratocytes. These keratocytes have a potential for tissue engineering and cell therapy of various corneal pathologies. Full article

Keeping the global temperature rise below 2 degrees Celsius, as foreseen by the Paris Agreement, requires a new global roadmap for the energy transition. For this reason, the European Commission decided to directly involve local municipalities in reaching these objectives through multilevel, bottom-up actions for sustainable energy. The Covenant of Mayors is a very concrete demonstration of this trend of development and adoption of sustainable energy action plans (SEAP), rethinking the way cities operate and bringing them closer to energy self-sufficiency, with measures favouring local economic development and improving citizens’ quality of life. The numerous RES/RUE actions included in SEAPs at the regional level have led both to the request for huge funding and to increased complexity for regional managers to identify the best projects to be financed. To manage the multitude of data (emissions, energy consumption, cost, etc.) present in the SEAPs at a regional level, a web-based platform called Lex-energetica was developed. In this context, this paper aims to present a participatory supportive framework for the decision-making process involved in financing the SEAPs’ actions, considering the selection of sustainable Renewable Energy Sources (RES) and Rational Use of Energy (RUE) technologies. This study proposes a methodology based on two macro-phases: the first phase consists of a ranking evaluation of categories of areas of intervention based on the analytic hierarchy process, while the second identifies nine criteria, according to the domains corresponding to the three pillars of sustainability, to compare the most appropriate RES/RUE actions. Full article