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Keywords = Pd/Ag-cocatalyzed

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21 pages, 4617 KiB  
Article
Pd/Ag-Cocatalyzed Merging Intramolecular Oxidative Coupling and Cascade [4 + 2] Cycloaddition: Synthesis and Photophysical Properties of Novel Polycyclic N-Heterocycles Fused Naphthoquinones
by Yu Dong, Lin Chen, Han-Qing Wu, Li Xie, Jing-Hao Yu, Fan Yang, Yu-Ting Wang, Yu-Rong Liu, Guo-Wei Deng and Zhi-Fan Wang
Molecules 2024, 29(23), 5639; https://doi.org/10.3390/molecules29235639 - 28 Nov 2024
Cited by 1 | Viewed by 791
Abstract
We report a step-economic strategy for the direct synthesis of novel polycyclic N-heterocycle-fused naphthoquinones by merging intramolecular oxidative coupling and cascade [4 + 2] cycloaddition. In the protocol, mechanistic investigations suggest that the cascade reaction involves the intermediate spiro polycyclic N-heterocycles [...] Read more.
We report a step-economic strategy for the direct synthesis of novel polycyclic N-heterocycle-fused naphthoquinones by merging intramolecular oxidative coupling and cascade [4 + 2] cycloaddition. In the protocol, mechanistic investigations suggest that the cascade reaction involves the intermediate spiro polycyclic N-heterocycles and [4 + 2] cycloaddition processes. This protocol is featured with moderate to excellent yields, wide substrate scope, and divergent structures of products. In addition, the photophysical properties of the synthesized products were evaluated. These products exhibit interesting fluorescence properties, and surprisingly, the compounds have the ability to selectively recognize trifluoroacetic acid. Full article
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7 pages, 4013 KiB  
Communication
The Homocoupling Reaction of Aromatic Terminal Alkynes by a Highly Active Palladium(II)/AgNO3 Cocatalyst in Aqueous Media Under Aerobic Conditions
by Mengping Guo, Bo Chen, Meiyun Lv, Xiuling Zhou, Yongju Wen and Xiuli Shen
Molecules 2016, 21(5), 606; https://doi.org/10.3390/molecules21050606 - 10 May 2016
Cited by 14 | Viewed by 5092
Abstract
A new and efficient Pd(II)/AgNO3-cocatalyzed homocoupling of aromatic terminal alkynes is described. Various symmetrical 1,4-disubstituted-1,3-diynes are obtained in good to excellent yields. This protocol employs a loading with relatively low palladium(II) in aqueous media under aerobic conditions. Full article
(This article belongs to the Special Issue Palladium Catalysts 2016)
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