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Keywords = Myristica cinnamomea King

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7 pages, 3025 KB  
Communication
Quorum Sensing Inhibitory Activity of Giganteone A from Myristica cinnamomea King against Escherichia coli Biosensors
by Yasodha Sivasothy, Thiba Krishnan, Kok-Gan Chan, Siti Mariam Abdul Wahab, Muhamad Aqmal Othman, Marc Litaudon and Khalijah Awang
Molecules 2016, 21(3), 391; https://doi.org/10.3390/molecules21030391 - 21 Mar 2016
Cited by 8 | Viewed by 5780
Abstract
Malabaricones A–C (1–3) and giganteone A (4) were isolated from the bark of Myristica cinnamomea King. Their structures were elucidated and characterized by means of NMR and MS spectral analyses. These isolates were evaluated for their anti-quorum sensing activity using quorum sensing biosensors, [...] Read more.
Malabaricones A–C (1–3) and giganteone A (4) were isolated from the bark of Myristica cinnamomea King. Their structures were elucidated and characterized by means of NMR and MS spectral analyses. These isolates were evaluated for their anti-quorum sensing activity using quorum sensing biosensors, namely Escherichia coli [pSB401] and Escherichia coli [pSB1075], whereby the potential of giganteone A (4) as a suitable anti-quorum sensing agent was demonstrated. Full article
(This article belongs to the Section Natural Products Chemistry)
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