Sign in to use this feature.

Years

Between: -

Subjects

remove_circle_outline
remove_circle_outline
remove_circle_outline

Journals

Article Types

Countries / Regions

Search Results (1)

Search Parameters:
Keywords = Lawsonella clevelandensis

Order results
Result details
Results per page
Select all
Export citation of selected articles as:
13 pages, 490 KiB  
Article
First Animal Source Metagenome Assembly of Lawsonella clevelandensis from Canine External Otitis
by Adrienn Gréta Tóth, Norbert Solymosi, Miklós Tenk, Zsófia Káldy and Tibor Németh
Pathogens 2025, 14(5), 465; https://doi.org/10.3390/pathogens14050465 - 10 May 2025
Viewed by 1003
Abstract
External otitis is one of the most common conditions in dogs to be presented to the veterinarian. Moreover, the disorder is often challenging to manage. The range and role of microorganisms involved in the pathogenesis are currently not fully understood. Therefore, the condition [...] Read more.
External otitis is one of the most common conditions in dogs to be presented to the veterinarian. Moreover, the disorder is often challenging to manage. The range and role of microorganisms involved in the pathogenesis are currently not fully understood. Therefore, the condition has been studied using third-generation sequencing (Oxford Nanopore Technology) to gain a more complete picture of the pathogens involved. Throughout the metagenome assembly of a sample from the ear canal of an 11-year-old female Yorkshire terrier suffering from chronic external otitis, a genome of Lawsonella clevelandensis was compiled. To our knowledge, this result is the first of its type of animal origin. The outcome of the assembly is a single circular chromosome with a length of 1,909,339 bp and 1727 predicted genes. One open reading frame associated with antimicrobial resistance could have been identified. Comparing all available genomes, the species can be associated with three main genome clusters. The finding contributes to the extending knowledge bank about this often-overlooked pathogen and raises attention to the role of nanopore sequencing by the identification and characterization of microorganisms that are difficult to culture. Full article
(This article belongs to the Section Bacterial Pathogens)
Show Figures

Figure 1

Back to TopTop