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Keywords = IF-associated liver disease

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11 pages, 588 KB  
Review
A Multidisciplinary Approach to the Classification and Management of Intestinal Failure: Knowledge in Progress
by Sol Ramírez-Ochoa, Luis Asdrúval Zepeda-Gutiérrez, Mauricio Alfredo Ambriz-Alarcón, Berenice Vicente-Hernández, Gabino Cervantes-Guevara, Karla D. Castro Campos, Karla Valencia-López, Gabino Cervantes-Pérez, Mariana Ruiz-León, Francisco Javier Hernández-Mora, Tania Elizabeth Cervantes-Nápoles, María Elena Flores-Villavicencio, Sandra O. Sánchez-Sánchez and Enrique Cervantes-Pérez
Diagnostics 2024, 14(19), 2114; https://doi.org/10.3390/diagnostics14192114 - 24 Sep 2024
Cited by 1 | Viewed by 2760
Abstract
Intestinal failure (IF) is a debilitating condition characterized by the insufficient function of the gastrointestinal tract to absorb nutrients and fluids essential for life. This review consolidates recent advancements and challenges in managing IF among adult and pediatric populations, highlighting differences in etiology, [...] Read more.
Intestinal failure (IF) is a debilitating condition characterized by the insufficient function of the gastrointestinal tract to absorb nutrients and fluids essential for life. This review consolidates recent advancements and challenges in managing IF among adult and pediatric populations, highlighting differences in etiology, management, and outcomes. Over the recent years, significant strides have been made in the nutritional and medical management of IF, significantly reducing mortality rates and improving the quality of life for patients. Key advancements include the development and availability of glucagon-like peptide-2 (GLP-2) analogs, improved formulations of parenteral nutrition, and the establishment of specialized interdisciplinary centers. Short bowel syndrome (SBS) remains the predominant cause of IF globally. The pediatric segment is increasingly surviving into adulthood, presenting unique long-term management challenges that differ from adult-onset IF. These include the need for tailored nutritional support, management of IF-associated liver disease, and addressing growth and neurodevelopmental outcomes. The therapeutic landscape for IF continues to evolve with the development of new treatment modalities and better understanding of the condition’s pathophysiology. However, disparities in treatment outcomes between children and adults suggest the need for age-specific management strategies. This review underscores the importance of a nuanced approach to IF, incorporating advancements in medical science with a deep understanding of the distinct needs. Full article
(This article belongs to the Special Issue Advances in the Diagnosis and Management of Digestive System Diseases)
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36 pages, 5124 KB  
Review
Metabolic and Nutritional Issues after Lower Digestive Tract Surgery: The Important Role of the Dietitian in a Multidisciplinary Setting
by Alejandra Utrilla Fornals, Cristian Costas-Batlle, Sophie Medlin, Elisa Menjón-Lajusticia, Julia Cisneros-González, Patricia Saura-Carmona and Miguel A. Montoro-Huguet
Nutrients 2024, 16(2), 246; https://doi.org/10.3390/nu16020246 - 12 Jan 2024
Cited by 12 | Viewed by 26083
Abstract
Many patients undergo small bowel and colon surgery for reasons related to malignancy, inflammatory bowel disease (IBD), mesenteric ischemia, and other benign conditions, including post-operative adhesions, hernias, trauma, volvulus, or diverticula. Some patients arrive in the operating theatre severely malnourished due to an [...] Read more.
Many patients undergo small bowel and colon surgery for reasons related to malignancy, inflammatory bowel disease (IBD), mesenteric ischemia, and other benign conditions, including post-operative adhesions, hernias, trauma, volvulus, or diverticula. Some patients arrive in the operating theatre severely malnourished due to an underlying disease, while others develop complications (e.g., anastomotic leaks, abscesses, or strictures) that induce a systemic inflammatory response that can increase their energy and protein requirements. Finally, anatomical and functional changes resulting from surgery can affect either nutritional status due to malabsorption or nutritional support (NS) pathways. The dietitian providing NS to these patients needs to understand the pathophysiology underlying these sequelae and collaborate with other professionals, including surgeons, internists, nurses, and pharmacists. The aim of this review is to provide an overview of the nutritional and metabolic consequences of different types of lower gastrointestinal surgery and the role of the dietitian in providing comprehensive patient care. This article reviews the effects of small bowel resection on macronutrient and micronutrient absorption, the effects of colectomies (e.g., ileocolectomy, low anterior resection, abdominoperineal resection, and proctocolectomy) that require special dietary considerations, nutritional considerations specific to ostomized patients, and clinical practice guidelines for caregivers of patients who have undergone a surgery for local and systemic complications of IBD. Finally, we highlight the valuable contribution of the dietitian in the challenging management of short bowel syndrome and intestinal failure. Full article
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