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2 Results Found

  • Article
  • Open Access
1 Citations
2,999 Views
14 Pages

Pathophysiological and Clinical Significance of Crotalus durissus cascavella Venom-Induced Pulmonary Impairment in a Murine Model

  • Ricardo G. Figueiredo,
  • Marcos Lázaro da Silva Guerreiro,
  • Elen Azevedo,
  • Mateus Souza de Moura,
  • Soraya Castro Trindade,
  • José de Bessa and
  • Ilka Biondi

14 April 2023

Crotalus venom has broad biological activity, including neurotoxic, myotoxic, hematologic, and cytotoxic compounds that induce severe systemic repercussions. We evaluated the pathophysiological and clinical significance of Crotalus durissus cascavell...

  • Article
  • Open Access
6 Citations
11,506 Views
24 Pages

Modulation of the Pharmacological Activities of Secretory Phospholipase A2 from Crotalus durissus cascavella Induced by Naringin

  • Marcelo L. Santos,
  • Daniela O. Toyama,
  • Simone C. B. Oliveira,
  • Camila A. Cotrim,
  • Eduardo B. S. Diz-Filho,
  • Fábio H. R. Fagundes,
  • Veronica C. G. Soares,
  • Ricardo Aparicio and
  • Marcos H. Toyama

18 January 2011

In this work we have characterized the action of the naringin, a flavonoid found in grapefruit and known for its various pharmacological effects, which include antioxidant blood lipid lowering and anticancer activity, on the structure and biochemical...