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Keywords = Boix-Ochoa score

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12 pages, 645 KiB  
Article
Is There a Potential Link between Gastroesophageal Reflux Disease and Recurrent Respiratory Tract Infections in Children?
by Vasile Valeriu Lupu, Gabriela Stefanescu, Ana Maria Laura Buga, Lorenza Forna, Elena Tarca, Iuliana Magdalena Starcea, Cristina Maria Mihai, Laura Florescu, Andrei Tudor Cernomaz, Adriana Mocanu, Viorel Tarca, Aye Aung Thet and Ancuta Lupu
Diagnostics 2023, 13(13), 2310; https://doi.org/10.3390/diagnostics13132310 - 7 Jul 2023
Cited by 6 | Viewed by 2364
Abstract
Background: The implications of gastroesophageal reflux disease in respiratory tract infections have been investigated over time. The aim of our study was to evaluate the relationship between these two pathologic entities and the outcome after proper antireflux treatment. Methods: A group of 53 [...] Read more.
Background: The implications of gastroesophageal reflux disease in respiratory tract infections have been investigated over time. The aim of our study was to evaluate the relationship between these two pathologic entities and the outcome after proper antireflux treatment. Methods: A group of 53 children with recurrent respiratory tract infections admitted in the gastroenterology clinic of a children’s hospital in North-East Romania was investigated for gastroesophageal reflux disease through 24 h pH-metry. Those with a Boix-Ochoa score higher than 11.99 received proton pump inhibitor treatment and were reevaluated after 2 months. Results: A total of 41 children were found with a positive Boix-Ochoa score. After 2 months of antireflux therapy, eight patients still had a positive Boix-Ochoa score. Conclusions: Recurrent respiratory tract infections with symptoms resistant to treatment should be considered a reason to investigate for gastroesophageal reflux, because the symptoms may be due to micro- or macro-aspiration of the gastric refluxate or to an esophageal-bronchial reflex mediated through the vagal nerve. Full article
(This article belongs to the Special Issue Pediatric Gastrointestinal Diseases: Diagnosis and Management)
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8 pages, 1063 KiB  
Article
Gastroesophageal Reflux in Children with Asthma
by Vasile Valeriu Lupu, Ingrith Miron, Elena Tarca, Laura Mihaela Trandafir, Dana-Teodora Anton-Paduraru, Stefana Maria Moisa, Magdalena Starcea, Andrei Cernomaz, Lucian Miron and Ancuta Lupu
Children 2022, 9(3), 336; https://doi.org/10.3390/children9030336 - 2 Mar 2022
Cited by 17 | Viewed by 4032
Abstract
Background: Nowadays it is considered that a specific causal relationship exists between asthma and gastroesophageal reflux (GER), because of the aspiration of gastric refluate which leads to and maintain spasticity even real crisis of paroxystic expiratory dyspnea. This study explores this relationship and [...] Read more.
Background: Nowadays it is considered that a specific causal relationship exists between asthma and gastroesophageal reflux (GER), because of the aspiration of gastric refluate which leads to and maintain spasticity even real crisis of paroxystic expiratory dyspnea. This study explores this relationship and evaluates the results after treatment. Methods: 56 children diagnosed with asthma, hospitalized in a regional center of pediatric gastroenterology in Northeast Romania, underwent 24-hour continuous esophageal pH monitoring in order to establish the presence of GER. The Boix-Ochoa score was used to interpret the results. Proton pump inhibitors were administered to those with GER and the patients were reevaluated after 2 months. Results: 39 patients (69.64%) had GER, with a Boix-Ochoa score above normal (N < 11.99), and 17 patients (30.36%) had normal score. After administering proton pump inhibitors for 2 months, 7 patients still had high Boix-Ochoa score (17.95%). The result of this analysis shows that the presence of asthma increases the chance of GER by 2.86 times. Conclusions: In children with asthma we have to look for GER in order to treat, because it can help the treatment of asthma or even solve some cases resistant to standard treatment. Full article
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