Search Results (7)

College sports is a multi-billion-dollar business, and universities are looking for ways to remain competitive, including recruiting and retaining athletes from historically underrepresented groups to predominantly white institutions (PWI), many of which have a documented history of excluding non-white students, including blacks, indigenous peoples, and other people of color (often referred to as BIPOC). This article will examine the legacy of the racist teachings, past controversies, and compromises of the Church of Jesus Christ of Latter-day Saints (LDS, Mormons) along with persistent struggles to shake off its 130-year-old racist past in efforts for its flagship school, Brigham Young University, to stay competitive in the lucrative Big 12 Athletic Conference. Deeply ingrained in the LDS culture is a politic of religious conservatism. Politics has often been intertwined with organized religion with much influence, and the LDS faith is no different. The cumulation of these interlocking systems generates thoughts, attitudes, and feelings that foster a racial climate at Brigham Young University where black students have reported feeling unsafe and unsupported. While this is a well-documented problem at predominately white institutions (PWIs) across the country, BYU is in many ways unique, given the discriminatory overt policies and practices employed for generations. We contend that the LDS Church’s history of racial marginalization and exclusion of black people made its way into the sports consciousness of the church’s flagship school and is not likely to change anytime soon. Understanding religion in the tradition of Charles Long as an orientation and utilizing Derrick Bell’s notion of racial realism are critical to our analyses. The confluence of politics, religion, race, and sport cannot be easily untangled. Full article

Candida parapsilosis carbonyl reductases (CpRCR) have been widely used for the reductive conversion of ketone precursors and chiral alcohol products in pharmaceutical industries. The enzymatic enantioselectivity is believed to be related to the shape complementation between the cavities in the enzymes and the substitutions of the ketone substrates. In this work, we reported an unexpected enantioselectivity in the enzyme reductions of dihydrofuran-3(2H)-one (DHF) to (S)-tetrahydrofuran-3-ol (DHF-ol, enantiomeric excess: 96.4%), while dihydrothiophen-3(2H)-one substrate (DHT) was unproductive under the same experimental conditions. To rationalize the exclusive S-configuration and the specific reactivity of DHF, we carried out molecular dynamics simulations for the reacting complexations of DHF with CpRCR, and DHT with CpRCR. Our calculations indicate that DHF preferentially binds to the small cavity near L119, F285, and W286, while the large cavity near the α1 helix was mainly occupied by solvent water molecules. Moreover, the pre-reaction state analysis suggests that the pro-S conformations were more abundant than the pro-R, in particular for DHF. This suggests that the non-polar interaction of substrate C4-C5 methylene contacting the hydrophobic side-chains of L119-F285-W286, and the polar interaction of funanyl oxygen exposing the solvent environment play important roles in the enantioselectivity and reactivity. The phylogenetic tree of CpRCR homologues implies that a variety of amino acid combinations at positions 285 and 286 were available and thereby potentially useful for redesigning enantioselective reductions of 5-membered-ring heterocyclic ketones. Full article

Plant-produced volatile compounds play important roles in plant signaling and in the communication of plants with other organisms. Many plants emit green leaf volatiles (GLVs) in response to damage or attack, which serve to warn neighboring plants or attract predatory or parasitic insects to help defend against insect pests. GLVs include aldehydes, esters, and alcohols of 6-carbon compounds that are released rapidly following wounding. One GLV produced by maize (Zea mays) is the volatile (Z)-3-hexenal; this volatile is produced from the cleavage of (9Z,11E,15Z)-octadecatrienoic acid by hydroperoxide lyases (HPLs) of the cytochrome P450 CYP74B family. The specific HPL in maize involved in (Z)-3-hexenal production had not been determined. In this study, we used phylogenetics with known HPLs from other species to identify a candidate HPL from maize (ZmHPL). To test the ability of the putative HPL to produce (Z)-3-hexenal, we constitutively expressed the gene in Arabidopsis thaliana ecotype Columbia-0 that contains a natural loss-of-function mutant in AtHPL and examined the transgenic plants for restored (Z)-3-hexenal production. Volatile analysis of leaves from these transgenic plants showed that they did produce (Z)-3-hexenal, confirming that ZmHPL can produce (Z)-3-hexenal in vivo. Furthermore, we used gene expression analysis to show that expression of ZmHPL is induced in maize in response to both wounding and the insect pests Spodoptera frugiperda and Spodoptera exigua. Our study demonstrates that ZmHPL can produce GLVs and highlights its likely role in (Z)-3-hexenal production in response to mechanical damage and herbivory in maize. Full article

While access to higher education has grown over the past few years, significant barriers exist for nontraditional students attempting to prepare for and complete postsecondary education. For these students, the traditional methods for acknowledging student achievement do not always work. This research explored the impact of earning professional certificates on nontraditional students’ confidence, motivation, and persistence. Specifically, this study evaluated the matriculation rates between two cohorts of students who participated in the online PathwayConnect program. The mixed-method study found that matriculation rates for students who were encouraged to earn a certificate increased compared to those who followed a traditional path. Analysis of these results suggests that earning a certificate increased students’ confidence and motivation to persist in school. Students reported that (a) earning certificates represented a significant achievement and encouraged them to earn more, (b) the certificate allowed participants to obtain better employment, and (c) the satisfaction of this accomplishment improved their desire to acquire new skills. This approach seemed to positively impact on the development of a strong support network that helped diminish some of the traditional barriers to matriculation. Institutions seeking to improve matriculation rates and student persistence might consider providing professional certificates programs in addition to current academic offerings. Full article

Internet service providers (ISPs) conduct their business by providing Internet access features to their customers. The COVID-19 pandemic has shifted most activity being performed remotely using an Internet connection. As a result, the demand for Internet services increased by 50%. This significant rise in the appeal of Internet services needs to be overtaken by a notable increase in the service quality provided by ISPs. Service quality plays a great role for enterprises, including ISPs, in retaining consumer loyalty. Thus, modelling ISPs’ service quality is of great importance. Since a common technique to reveal service quality is a timely and costly pencil survey-based method, this work proposes a framework based on the Sentiment Analysis (SA) of the Twitter dataset to model service quality. The SA involves the majority voting of three machine learning algorithms namely Naïve Bayes, Multinomial Naïve Bayes and Bernoulli Naïve Bayes. Making use of Thaicon’s service quality metrics, this work proposes a formula to generate a rating of service quality accordingly. For the case studies, we examined two ISPs in Indonesia, i.e., By.U and MPWR. The framework successfully extracted the service quality rate of both ISPs, revealing that By.U is better in terms of service quality, as indicated by a service quality rate of 0.71. Meanwhile, MPWR outperforms By.U in terms of customer service. Full article

Each year in the United States, 7000 to 30,000 children experience their parent’s suicide. Due to the stigma associated with suicide, feelings of guilt, and intense grief, surviving family members avoid talking about suicide. Over time, children struggle with confusion and intense emotions associated with their parent’s suicide. In this study, seven adults, who reported being younger than six years old at the time of their father’s suicide, participated in individual semi-structured interviews. Participants’ responses highlight the challenges that young children face due to limited memories of their deceased parent. Interviews concluded with an opportunity for participants to review and express their impressions of 10 children’s picture books. Participants offered impressions about how these books may or may not be helpful in supporting young child survivors. Implications for applied practice include considering how children’s literature may open communication and assist children in navigating Worden’s tasks of grief: (a) accepting the reality of their parent’s death; (b) facing the grief and pain; (c) adapting to life changes due to their father’s suicide, in particular adapting to altered family relationships; and (d) building memories of the deceased loved one, when possible, to ensure healthy attachment to the deceased parent. Participants’ insights provide considerations for selecting children’s literature for bibliotherapy. Due to young child survivors’ increased risk for attempting and completing suicide, supporting child survivors of parent suicide not only addresses postvention needs but aligns with suicide prevention. Full article

Germinated seed from cereal crops including barley (Hordeum vulgare L.) is an important tissue to extract RNA and analyze expression levels of genes that control aspects of germination. These tissues are rich in polysaccharides and most methods for RNA extraction are not suitable to handle the excess polysaccharides. Here, we compare the current methods for RNA extraction applicable to germinated barley tissue. We found that although some of these standard methods produced high-quality RNA, the process of extraction was drastically slow, mostly because the frozen seed tissue powder from liquid N₂ grinding became recalcitrant to buffer mixing. Our suggested modifications to the protocols removed the need for liquid N₂ grinding and significantly increased the output efficiency of RNA extraction. Our modified protocol has applications in other cereal tissues rich in polysaccharides, including oat. Full article