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Keywords = 2-tosylalkyl phenols

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9 pages, 2514 KB  
Brief Report
Straightforward Synthesis of Bifunctional Phosphorus Phenols via Phosphination of In Situ Generated o-Quinone Methides
by Zhangpei Chen, Qinglong Shi, Gongshu Wang, Siwen Chen and Jianshe Hu
Molecules 2018, 23(6), 1240; https://doi.org/10.3390/molecules23061240 - 23 May 2018
Cited by 6 | Viewed by 4305
Abstract
An efficient and practical approach towards bifunctional phosphorus phenols has been developed through a reaction of diphenylphosphine oxide and the o-quinone methides in situ generated from 2-tosylalkyl phenols under basic conditions. This protocol features simple experimental procedures under mild conditions and is [...] Read more.
An efficient and practical approach towards bifunctional phosphorus phenols has been developed through a reaction of diphenylphosphine oxide and the o-quinone methides in situ generated from 2-tosylalkyl phenols under basic conditions. This protocol features simple experimental procedures under mild conditions and is easily scaled up. With this method, a variety of diarylmethyl phosphine oxides can be produced with up to 92% yield. Full article
(This article belongs to the Section Organic Chemistry)
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