Search Results (7)

One of the practical methods for examining the stability and dynamical behaviour of non-linear systems is weakly non-linear stability analysis. Time-varying gravitational acceleration and triple-diffusive convection play a significant role in the formation of acceleration, inducing some dynamics in the industry. With an emphasis on the natural Rayleigh–Bernard convection, more is needed on the significance of a modulated gravitational field on the heat and mass transfer due to triple convection focusing on weakly non-linear stability analysis. The Newtonian fluid layers were heated, salted and saturated from below, causing the bottom plate’s temperature and concentration to be greater than the top plate’s. In this study, the acceleration due to gravity was assumed to be time-dependent and comprised of a constant gravity term and a time-dependent gravitational oscillation. More so, the amplitude of the modulated gravitational field was considered infinitesimal. The case in which the fluid layer is infinitely expanded in the x-direction and between two concurrent plates at $z=0$ and $z=d$ was considered. The asymptotic expansion technique was used to retrieve the solution of the Ginzburg–Landau differential equation (i.e., a system of non-autonomous partial differential equations) using the software MATHEMATICA 12. Decreasing the amplitude of modulation, Lewis number, Rayleigh number and frequency of modulation has no significant effect on the Nusselt number proportional to heat-transfer rates ($Nu$), Sherwood number proportional to mass transfer of solute 1 ($S{h}_1$) and Sherwood number proportional to mass transfer of solute 2 ($S{h}_2$) at the initial time. The crucial Rayleigh number rises in value in the presence of a third diffusive component. The third diffusive component is essential in delaying the onset of convection. Full article

Diabetes is a major health challenge, and it is linked to a number of serious health issues, including cardiovascular disease (heart attack and stroke), diabetic nephropathy (kidney damage or failure), and birth defects. The detection of glucose has a direct and significant clinical importance in the management of diabetes. Herein, we demonstrate the application of in-situ synthesized Ti₂C-TiO₂ MXene nanocomposite for high throughput non-enzymatic electrochemical sensing of glucose. The nanocomposite was synthesized by controlled oxidation of Ti₂C-MXene nanosheets using H₂O₂ at room temperature_. The oxidation results in the opening up of Ti₂C-MXene nanosheets and the formation of TiO₂ nanocrystals on their surfaces as revealed in microscopic and spectroscopic analysis. Nanocomposite exhibited considerably high electrochemical response than parent Ti₂C MXene, and hence utilized as a novel electrode material for enzyme-free sensitive and specific detection of glucose. Developed nanocomposite-based non-enzymatic glucose sensor (NEGS) displays a wide linearity range (0.1 µM-200 µM, R² = 0.992), high sensitivity of 75.32 μA mM⁻¹ cm⁻², a low limit of detection (0.12 μM) and a rapid response time (~3s). NEGS has further shown a high level of repeatability and selectivity for glucose in serum spiked samples. The unveiled excellent sensing performance of NEGS is credited to synergistically improved electrochemical response of Ti₂C MXene and TiO₂ nanoparticles. All of these attributes highlight the potential of MXene nanocomposite as a next-generation NEGS for on the spot mass screening of diabetic patients. Full article

In over eighty years, despite successive antibiotics discoveries, the rapid advent of multidrug resistance among bacterial pathogens has jolted our misapprehension of success over them. Resistance is spreading faster than the discovery of new antibiotics/antimicrobials. Therefore, the search for better antimicrobials/additives becomes prudent. A water-soluble curcumin derivative (Cur_aq) was synthesised, employing a Cu (I) catalysed 1, 3-cyclo addition reaction; it has been evaluated as a potential treatment for multidrug-resistant isolates and as an antibiotic adjuvant for meropenem against hypervirulent multidrug-resistant Klebsiella pneumoniae isolates. We also investigated its solubility and effect over carbapenemase activity. Additionally, we investigated its impact on the AcrAB-TolC system. We found that Cur_aq inhibited bacterial growth at a minimal concentration of 16 µg/mL; at a 32 µg/mL concentration, it killed bacterial growth completely. Only nine (9.4%) Klebsiella isolates were sensitive to meropenem; however, after synergising with Cur_aq (8 µg/mL), 85 (88.54%) hvKP isolates became sensitive to the drug. The Cur_aq also inhibited the AcrAB-TolC efflux system at 1 µg/mL concentration by disrupting the membrane potential and causing depolarisation. The kinetic parameters obtained also indicated its promise as a carbapenemase inhibitor. These results suggest that Cur_aq can be an excellent drug candidate as a broad-spectrum antibacterial and anti-efflux agent. Full article

In this article, a study on the stability of Walter-B viscoelastic fluid in the highly permeable porous medium under the rotational speed modulation is presented. The impact of rotational modulation on heat transport is performed through a weakly nonlinear analysis. A perturbation procedure based on the small amplitude of the perturbing parameter is used to study the combined effect of rotation and permeability on the stability through a porous medium. Rayleigh–Bénard convection with the Coriolis expression has been examined to explain the impact of rotation on the convective flow. The graphical result of different parameters like modified Prandtl number, Darcy number, Rayleigh number, and Taylor number on heat transfer have discussed. Furthermore, it is found that the modified Prandtl number decelerates the heat transport which may be due to the combined effect of elastic parameter and Taylor number. Full article

Membranes of 4-tert-butylcalix(8)arene-octaacetic acid octaethyl ester (I) as an electroactive material, sodium tetraphenyl borate (NaTPB) as an anion excluder, and tri-n-butyl phosphate (TBP) as a solvent mediator in poly(vinyl chloride) (PVC) matrix have been tried for a strontium-selective sensor. The best performance was exhibited by the membrane having a composition 5:100:150:2 (I: PVC: TBP: NaTPB (w/w)). This sensor exhibits a good potentiometric response to Sr²⁺ over a wide concentration range (3.2 × 10 ^–5 –1.0 × 10 ^–1 M) with a Nernstian slope (30 mV/ decade). The response time of the sensor is 10 s and it has been used for a period of four months without any drift in potentials. The selectivity coefficient values are in the order of 0.01 for mono-, bi-, and trivalent cations which indicate a good selectivity for Sr²⁺ over a large number of cations. The useful pH range for the sensor was found to be 3-10 and it works well in mixtures with non-aqueous content up to 25 % (v/v). The sensor has been used as an indicator electrode in the potentiometric titration of Sr²⁺ against EDTA. Full article

The tetramethyldibenzocyclam derivative, was synthesized and characterized and was used for fabrication of potentiometric sensor for Ni²⁺ metal ion. 5,7,8,14-tetramethyldibenzo[b,i]-1,4,8,11-tetrazacyclotetradecanenickel(II)chloride, ([Ni(Me₄Bzo₂[14]ane N₄)]Cl₂) (II) was obtained in good yield as orange red salt by Fe/HCl reduction of the corresponding tetraazaannulene complex [Ni(Me4Bzo₂taa)], (I). Membrane having [Ni(Me₄Bzo₂[14]aneN₄)]Cl₂ (II) as electroactive material, sodium tetraphenylborate (NaTPB) as an anion discriminator, dibutyl butylphosphonate (DBBP) as plasticizer in PVC matrix in the percentage ratio 5.0:2.5:200:200 (II:NaTPB:DBBP:PVC)(w/w) exhibits a linear response to Ni²⁺ in the concentration range 7.0×10^-6- 1.0×10^-1M with a slope of 29.8±0.2 mV/decade of activity and a fast response time of 12s. The sensor works well in the pH range 2.0-7.6 and can be satisfactorily used in presence of 40% (v/v) methanol, ethanol or acetone. The sensor is highly selective for Ni²⁺ over a large number of mono-, biand trivalent cations. The sensor has been successfully used as indicator electrode in the potentiometric titration of Ni²⁺ against EDTA. These electrodes can be used to determine the concentration of Ni²⁺ in real samples. Full article

Polyvinyl chloride (PVC) membrane electrodes based on porphyrin 5,10,15,20-tetrakis(4methoxyphenyl)porphyrinatocobalt (TMOPP-Co) (I) incorporating sodium tetra phenyl borate (NaTPB) as anion excluder and dibutyl phthalate (DBP), dioctyl phthalate (DOP), dibutyl butyl phosphonate (DBBP), tri-n-butyl phosphate (TBP), and 1-chloronaphthalene (CN) as plasticizing solvent mediators were prepared and tested for selective detection of molybdate ions. The membrane having anion excluder, NaTPB and DBP as plasticizer (membrane no. 2) proved to be best in terms of working concentration range 5.0×10^-5 – 1.0×10^-1M with a near – Nernstian slope of 32.0±1.0 mV/decade of activity over the pH range 5.4- 10.5. The response time of this sensor is 18s with a lifetime of about 4 months. The sensor can be used in non-aqueous medium with no significant change in the value of slope or working concentration range for the estimation of MoO₄^2- in solutions having up to 25% (v/v) non-aqueous fraction. Full article