Search Results (2)

This study investigated the effects of dietary Gonadotropin-releasing hormone (GnRH) and domperidone on the reproductive performance of Devario devario during a 40-day trial. Five treatment groups received varying doses of GnRH (100, 50, 25, 12.5 µg/kg body weight) in combination with domperidone (50, 25, 12.5, 6.25 mg/kg body weight), embossed in a gel-based diet alongside a control group without the exogenous hormones. Reproductive performance was examined by measuring the gonadosomatic index, fecundity, reproductive hormone levels, and histological features of the gonads, blood parameters, and antioxidant enzyme activity. The T1 group (100 µg GnRH + 50 mg domperidone) exhibited the highest GSI in both sexes. The histological analysis of testes from T1, T2 (50 µg GnRH + 25 mg domperidone), and T3 (25 µg GnRH + 12.5 mg domperidone) groups revealed an increased presence of late-stage spermatids and spermatozoa. In females, the T2 group produced the highest proportion of advanced-stage oocytes and demonstrated the greatest absolute fecundity (1300 ± 23 eggs). However, the control group showed the highest fertilization and hatching rates. Testosterone levels were significantly elevated in the T3 group, while vitellogenin levels increased in the T1 and T2 groups. Antioxidant enzyme activity varied, with the T1 group displaying higher superoxide dismutase activity in gills and liver, and the T2 group showing increased SOD activity in muscle and brain. Improvements in haematological parameters were observed across all treatments. These results suggest that an optimal dose of 50 µg GnRH + 25 mg domperidone can enhance reproductive performance in D. devario. Full article

The fourth industrial revolution, fueled by automation and digital technology advancements, enables us to manage manufacturing systems effectively. Its deployment in enterprises has now become increasingly important in developed and emerging economies. Many experts believe that barriers associated with Industry 4.0 implementation are critical to its success. Therefore, this study aimed to identify the major hurdles to Industry 4.0 adoption and reveal their interrelationships. Initially, the literature was thoroughly studied to determine the sixteen barriers impeding I4.0 adoption. Then, based on experts’ opinions, an integrated fuzzy-DEMATEL approach was utilized to examine the most significant challenges to I4.0 deployment. The results demonstrated the distribution of barriers in which the economic dimension played a decisive role, affecting technological, regulatory, and organizational dimensions. As observed in the barrier mapping, the lack of qualified workforce was a typical adoption barrier. Finally, the mitigation strategies developed would help managers to overcome the identified critical obstacles. Full article