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Authors = Mohan S. M. Rawat

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31 pages, 5217 KiB  
Review
Theranostic Nanomedicines for the Treatment of Cardiovascular and Related Diseases: Current Strategies and Future Perspectives
by Natasha Manners, Vishnu Priya, Abhishesh Kumar Mehata, Manoj Rawat, Syam Mohan, Hafiz A. Makeen, Mohammed Albratty, Ali Albarrati, Abdulkarim M. Meraya and Madaswamy S. Muthu
Pharmaceuticals 2022, 15(4), 441; https://doi.org/10.3390/ph15040441 - 1 Apr 2022
Cited by 24 | Viewed by 5421
Abstract
Cardiovascular and related diseases (CVRDs) are among the most prevalent chronic diseases in the 21st century, with a high mortality rate. This review summarizes the various nanomedicines for diagnostic and therapeutic applications in CVRDs, including nanomedicine for angina pectoris, myocarditis, myocardial infarction, pericardial [...] Read more.
Cardiovascular and related diseases (CVRDs) are among the most prevalent chronic diseases in the 21st century, with a high mortality rate. This review summarizes the various nanomedicines for diagnostic and therapeutic applications in CVRDs, including nanomedicine for angina pectoris, myocarditis, myocardial infarction, pericardial disorder, thrombosis, atherosclerosis, hyperlipidemia, hypertension, pulmonary arterial hypertension and stroke. Theranostic nanomedicines can prolong systemic circulation, escape from the host defense system, and deliver theranostic agents to the targeted site for imaging and therapy at a cellular and molecular level. Presently, discrete non-invasive and non-surgical theranostic methodologies are such an advancement modality capable of targeted diagnosis and therapy and have better efficacy with fewer side effects than conventional medicine. Additionally, we have presented the recent updates on nanomedicine in clinical trials, targeted nanomedicine and its translational challenges for CVRDs. Theranostic nanomedicine acts as a bridge towards CVRDs amelioration and its management. Full article
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4 pages, 188 KiB  
Short Note
Synthesis and Characterization of a Novel 2-Pyrazoline
by Pramod Singh, Jagmohan S. Negi, Geeta Joshi Nee Pant, Mohan S. M. Rawat and Asha Budakoti
Molbank 2009, 2009(3), M614; https://doi.org/10.3390/M614 - 10 Aug 2009
Cited by 8 | Viewed by 9730
Abstract
Reaction of dibenzalacetone with hydrazine hydrate and formic acid yielded a novel 2-pyrazoline 1, characterized by ESI-MS, FT-IR, UV, 1HNMR and 13CNMR data and microanalysis. Full article
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